Results 71 to 80 of about 1,170,336 (314)

Physical Therapy Training Assistance for Inclusion Groups of Persons with Disabilities in Ngawonggo Village, Malang Regency

E-Dimas
Inclusive design provides space for minorities, namely people with disabilities, to have equal rights and obligations, equal dignity and status, and have the same role and position in the life of the village community.
Marsudi Dedi Putra, Mukhammad Soleh, Himawan Estu Bagijo, Regithai Putri Erlanha, Siti Naharotun Nikmah   +4 more
doaj   +1 more source

Director’s Duties in Groups of Companies – Legalizing the Interest of the Group at the European Level

European Company and Financial Law Review, 2013
The Action Plan of the European Commission of December 2012 on “European company law and corporate governance – a modern legal framework for more engaged shareholders and sustainable companies” mentioned that “the Commission will, in 2014, come with an initiative to improve both the information available on groups and recognition of the concept of ...
openaire   +2 more sources

Duty and Defiance: Women in Community-based Armed Groups in West Africa [PDF]

, 2021
This desk report explores how West African community-based armed groups (CBAGs) facilitate women’s engagement with politics, create avenues for female expressions of anger, commitment to community values and national identity, and enable women to push for change in their communities by opening spaces for female participation.
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Establishing the tasks of family health masters: a needs assessment study using Delphi technique

Journal of Medical Education and Development, 2014
Introduction: Professional duties are regarded as a base for developing the curriculum in a new course. The purpose of this study is to determine the professional duties of postgraduates of family health major according to the viewpoints of stakeholders. 
H Rezaei, AR Yosefi, N Yamani, GR sharifirad   +3 more
doaj  

The Twenty-Fifth Amendment: Law, History, and Recommendations for Reform [PDF]

, 2019
Handout for The Twenty-Fifth Amendment: Law, History, and Recommendations for Reform.https://ir.lawnet.fordham.edu/twentyfifth_amendment_miscellaneous/1002/thumbnail ...
Feerick, John D., Rogan, John
core   +1 more source

Underground railroads: citizen entitlements and unauthorized mobility in the antebellum period and today [PDF]

, 2010
In recent years, some scholars and prominent political figures have advocated the deepening of North American integration on roughly the European Union model, including the creation of new political institutions and the free movement of workers across ...
Archibold R. C., Blackett R. J.M., Bordewich F. M., Bordewich F. M., Brown H., Buchanan A., Cabrera L., Caney S., Carens J., Christie B., Clinton C., Coffin L., Ellingwood K., Eschbach K., Fox V., Franklin J. H., Graham O., Grossman D., Hadden S. E., Hayworth J. D., Hendricks T., Hoeffer M., Humez J., Huntington S., Innes S., Innes S., Kochhar R., Lowance M. I., Lucas R. E.B., Luis Cabrera, Manley J. P., McCombs B., Mitchell L. L., Moellendorf D., Pacheco J. F., Pastor R. A., Pastor R. A., Pickard M., Pogge T., Pollack A., Rawls J., Sen A., Still W., Tancredo T.   +43 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source