Results 31 to 40 of about 1,157 (207)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
HEDGE APPROXIMATORS AS PROFESSIONAL TOOLS OF GERMAN MASS MEDIA DISCOURSE
Дискурс профессиональной коммуникации, 2019 The purpose of this paper is the analysis of German mass media texts to investigate into hedge approximators. Synonymous analytical constructions eine Art … (a kind of); so etwas wie …; (so) etwas Ähnliches wie … are used to achieve certain pragmatic ...
E. L. Shubina
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
GEN.SG = NOM.PL: A mystery solved?
Linguistica Brunensia, 2016 This paper proposes an explanation for the identity of form between GEN.SG and NOM.PL. The paper first shows that the homonymy is attested in Czech as well as a number of other languages.
Pavel Caha
doaj
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Catalan Journal of LinguisticsIn this contribution, I present new evidence against any attempt to unify pseudo-partitive/quantificational and qualitative binominals (e.g., un grupo/montón de estudiantes ‘a group/lot of students’, una mierda de departamento ‘a shit of an apartment’).
Andrés Saab
doaj +1 more source
Academic Paper Titles and Their Dominating Patterns: a Russian-English Perspective
Вестник Волгоградского государственного университета: Серия 2. Языкознание, 2018 The article shows the key role that academic paper titles play in presenting paper contents and burden, and demonstrates cultural and linguistic differences between the academic style in Russian and in English.
Nadezhda K. Ryabtseva
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source