Results 101 to 110 of about 671,076 (285)

A Relation on Floer Homology Groups of Homology Handles

open access: yesTokyo Journal of Mathematics, 2006
The paper under review is to show a relationship on the rank of the Floer homology of integral homology handles. The Floer homology for homological \(S^2\times S^1\) is defined only for manifolds admitting a unique nontrivial \(SO(3)\), and its Floer relative index is no longer mod 8, but mod 4 period. The paper starts with observations from \textit{N.
openaire   +3 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Quandle and Biquandle Homology Calculation in R

open access: yesJournal of Open Research Software, 2018
In knot theory several knot invariants have been found over the last decades. This paper concerns itself with invariants of several of those invariants, namely the Homology of racks, quandles, biracks and biquandles.
Roger Fenn, Ansgar Wenzel
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Improvement in low-homology template-based modeling by employing a model evaluation method with focus on topology.

open access: yesPLoS ONE, 2014
Many template-based modeling (TBM) methods have been developed over the recent years that allow for protein structure prediction and for the study of structure-function relationships for proteins.
Wentao Dai   +6 more
doaj   +1 more source

Augmentation powers and group homology

open access: yesJournal of Pure and Applied Algebra, 2004
It is well-known that low-dimensional group homology provides a useful tool for studying lower central series, dimension subgroups and augmentation powers of group rings. The aim of this paper is to extend these methods to the study of transfinite augmentation powers and, more generally, to the study of two-sided ideals in group rings and the normal ...
Mikhailov, Roman, Passi, Inder Bir S.
openaire   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

The cyclic homology of the group rings

open access: yesCommentarii Mathematici Helvetici, 1985
Let G be a discrete group. For \(x\in G\), denote by \(G_ x\) the centralizer of x and by \(N_ x\) the quotient of \(G_ x\) by the subgroup generated by x. Write \(=_ f\cup _{\infty}\) for the decomposition of the conjugacy classes of G into classes \(\bar x\) with the property that ord x\(
openaire   +2 more sources

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