Results 221 to 230 of about 185,672 (304)
An ultraprocessive, accurate reverse transcriptase encoded by a metazoan group II intron. [PDF]
Zhao C, Liu F, Pyle AM.
europepmc +1 more source
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer +11 more
wiley +1 more source
Structure of a group II intron in complex with its reverse transcriptase. [PDF]
Qu G +7 more
europepmc +1 more source
The hidden regulators: Non‐coding RNAs in KMT2A‐rearranged acute lymphoblastic leukemia
Abstract Acute lymphoblastic leukemia (ALL) driven by KMT2A rearrangements (KMT2A‐r) is an aggressive hematologic malignancy with poor prognosis and a high incidence in infants. While KMT2A fusion proteins drive leukemogenesis through transcriptional dysregulation, recent discoveries have highlighted the pivotal role of non‐coding RNAs (ncRNAs) in ...
Maria Augusta Poersch +5 more
wiley +1 more source
Group II Intron Domain 5 Facilitates a trans-Splicing Reaction
Kevin A. Jarrell +2 more
openalex +2 more sources
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng +4 more
wiley +1 more source
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries [PDF]
Borecki, Ingrid +13 more
core +1 more source
Group II intron mobility and its gene targeting applications in prokaryotes and eukaryotes
Fanglei Zhuang
openalex +1 more source

