Results 51 to 60 of about 458,395 (307)
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
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Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
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The group inverse of a triangular matrix
Linear Algebra and its Applications, 1996 Block conditions are given for the group inverse of a triangular matrix over a field to exist. These involve the zero-nonzero Schur complement. Applications are given to idempotent matrices.
Xuzhou Chen, Robert E. Hartwig
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Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Perturbation of Dual Group Generalized Inverse and Group Inverse
SymmetrySymmetry plays a crucial role in the study of dual matrices and dual matrix group inverses. This paper is mainly divided into two parts. We present the definition of the spectral norm of a dual real matrix A^, (which is usually represented in the form A^=A+εA0, A and A0 are, respectively, the standard part and the infinitesimal part of A^) and two ...
Tianhe Jiang, Hongxing Wang, Yimin Wei
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Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
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Further representations and computations of the generalized Moore-Penrose inverse
AIMS Mathematics, 2023 The aim of this paper is to provide new representations and computations of the generalized Moore-Penrose inverse. Based on the Moore-Penrose inverse, group inverse, Bott-Duffin inverse and certain projections, some representations for the generalized ...
Kezheng Zuo, Yang Chen, Li Yuan
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About the group inverse and Moore-Penrose inverse of a product
Linear Algebra and its Applications, 1991 AbstractLet A be a matrix over a ring. Suppose that P, Q, P′, and Q′ are matrices over the ring such that P′PA=A=AQQ′. If A has group inverse A#, then PAQ has a group inverse iff AA#QPA+1−AA#is invertible. An analogous result for Moore-Penrose inverses is also given.
M.C. Gouveia, R. Puystjens
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Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
Additive Results of Group Inverses in Banach Algebras
MathematicsIn this paper, we present new presentations of group inverses for the sum of two group invertible elements in a Banach algebra. We then apply these results to block complex matrices.
Dayong Liu, Huanyin Chen
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