Results 61 to 70 of about 15,121,811 (367)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

ON CONDITIONS FOR MATRICES T SUCH THAT T-I AND I-T^(-1) ARE INVERSE H-MATRICES*

open access: yesBarekeng
In this article, we study an analogue of a classical result for M-matrices: if T - I is an invertible M-matrix, then both T and I - T-1 are also invertible M-matrices. We extend this implication to a broader class—inverse H-matrices.
Jeriko Gormantara   +3 more
doaj   +1 more source

Resistance Distance in H-Join of Graphs G1,G2,,Gk

open access: yesMathematics, 2018
In view of the wide application of resistance distance, the computation of resistance distance in various graphs becomes one of the main topics. In this paper, we aim to compute resistance distance in H-join of graphs G 1 , G 2 , … , G k
Li Zhang   +3 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Resistance Distance and Kirchhoff Index of the Corona-Vertex and the Corona-Edge of Subdivision Graph

open access: yesIEEE Access, 2018
The resistance distance is widely used in random walk, electronic engineering, and complex networks. One of the main topics in the study of the resistance distance is the computation problem.
Qun Liu, Jia-Bao Liu, Shaohui Wang
doaj   +1 more source

Inverse Synthetic Aperture Radar Sparse Imaging Exploiting the Group Dictionary Learning

open access: yesRemote Sensing, 2021
Sparse imaging relies on sparse representations of the target scenes to be imaged. Predefined dictionaries have long been used to transform radar target scenes into sparse domains, but the performance is limited by the artificially designed or existing ...
Changyu Hu   +3 more
doaj   +1 more source

When unit groups of continuous inverse algebras are regular Lie groups

open access: yes, 2012
It is a basic fact in infinite-dimensional Lie theory that the unit group G(A) of a continuous inverse algebra A is a Lie group. We describe criteria ensuring that the Lie group G(A) is regular in Milnor's sense.
Glockner, Helge, Neeb, Karl-Hermann
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Reduced group schemes as iterative differential Galois groups

open access: yes, 2019
This article is on the inverse Galois problem in Galois theory of linear iterative differential equations in positive characteristic. We show that it has an affirmative answer for reduced algebraic group schemes over any iterative differential field ...
Maurischat, Andreas
core   +1 more source

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