Results 31 to 40 of about 2,168,981 (303)

Case Summary: Sunman Group of Companies (Bangladesh) [PDF]

open access: yes, 2009
WRC report on its investigation of labor violations at companies owned by the Sunman group.
Worker Rights Consortium
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Use of structural adhesive joints in construction applications [PDF]

open access: yes, 2008
The Research Group of Materials Performance works in the development of structural adhesive joints and their performance in service in collaboration with some adhesive manufacturer companies.
Martínez Casanova, Miguel Ángel
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Development of an In Vitro Biopotency Assay for an AAV8 Hemophilia B Gene Therapy Vector Suitable for Clinical Product Release

open access: yesMolecular Therapy: Methods & Clinical Development, 2020
Gene therapy product release requires reliable and consistent demonstration of biopotency. In hemophilia B vectors, this is usually determined in vivo by measuring the plasma levels of the expressed human factor IX (FIX) transgene product in FIX knockout
Johannes Lengler   +8 more
doaj   +1 more source

Security and defence of mobile systems under impact [PDF]

open access: yes, 2008
The Group “Dynamics and Fracture of Structural Elements” offers its experience in Solid Mechanics analysis for the study of the impact protection of vehicles, aircrafts and persons.
Arias Hernández, Ángel   +1 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Adaptation of the performance control system of a technological piston hydrogen compressor to unstable operating conditions [PDF]

open access: yesОмский научный вестник: Серия "Авиационно-ракетное и энергетическое машиностроение"
Issues related to possible problems of the feasibility of operating the existing system for regulating the performance of a technological piston hydrogen compressor at a large chemical production and the relevance of its modernization are considered ...
V. L. Yusha   +3 more
doaj   +1 more source

Financialisation and physical investment: a global race to the bottom in accumulation? [PDF]

open access: yes, 2017
We estimate the effects of financialisation on physical investment in the developed and developing countries using panel data based on balance-sheets of publicly listed non-financial companies (NFCs) for the period 1995-2015.
Onaran, Özlem, Tori, Daniele
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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