Results 51 to 60 of about 2,168,981 (303)
YESTERDAY AND TODAY THE CENTER OF LABORATORY REFERENCE MATERIALS LTD «ECOHIM»
Стандартные образцы, 2017 The article describes the experience of the development and production of certified reference materials intended for metrological maintenance of ecological and analytical measurement and control oil product quality.
V. O. Arapov +2 more
doaj
Aquafed - another pressure group for private water [PDF]
, 2006 An analysis of the new private water lobby group, Aquafed, and the other forms of lobbying and pressure used by the private water ...
Hall, David, Hoedeman, Olivier
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Вестник урологии, 2018 Introduction. The main treatment component of asymptomatic bacteriuria, acute cystitis and pyelonephritis in pregnant women is antibiotic therapy, which in many patients is prescribed empirically.
K. L. Lokshin +4 more
doaj +1 more source
Application of Internal Control Systems in Organic Export Companies: Two Case Studies from Uganda [PDF]
, 2009 The organic agricultural sector of Uganda is considered the most developed in Africa with a total of 296,203 ha organic certified land and the most certified organic producers worldwide (206,800), 90% of whom are small scale farmers.
Preißel, Sara, Reckling, Moritz
core
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Engineering Reports, 2019 After the transmission of human viruses through plasma derivatives had been recognized in the early 1980s, virus inactivation and then removal steps have been implemented into their manufacturing processes.
Jean‐Baptiste Farcet +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Journal of Patient-Reported Outcomes, 2019 Background Capturing the impact of caring for patients with debilitating rare disease is important for understanding disease burden. We aimed to develop and validate an instrument to measure the impact on caregivers of caring for children with three ...
Magdalena Harrington +5 more
doaj +1 more source