Results 121 to 130 of about 7,795,742 (294)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Influence of pain duration and severity on oral health-related quality of life and patient satisfaction during adult treatment with clear aligners

open access: yesProgress in Orthodontics
Background This study aims to compare the impact of pain on quality of life and patient satisfaction during treatment with aligners. Methods Ninety-four subjects in active treatment were invited to answer self-reported questions concerning pain severity ...
Waleska Caldas   +4 more
doaj   +1 more source

Development and optimisation of a reception testing protocol designed to eliminate HCV in the UK prison population

open access: yesJHEP Reports
Background & Aims: Micro-elimination of hepatitis C virus (HCV) in high-risk populations is a feasible approach towards achieving the World Health Organization’s targets for viral hepatitis elimination by 2030.
Emily Mongale   +12 more
doaj   +1 more source

Improving the Skill of Group Guidance by Using Peer Practice Training (for the Student of Guidance and Counseling Program, Teacher Training and Education Faculty Universitas Muria Kudus in the Academic Year 2010/2011 [PDF]

open access: yes, 2014
Latar belakang penelitian adalah keterampilan mahasiswa dalam bimbingan kelompok masih rendah. Hal ini disebabkan metode perkuliahan masih diselenggarakan secara teoritis, dan seandainya praktik, maka mahasiswa belum diberi kesempatan menjadi pemimpin ...
Sucipto, S. (Sucipto)
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

CondenseNet: An Efficient DenseNet using Learned Group Convolutions

open access: yes, 2018
Deep neural networks are increasingly used on mobile devices, where computational resources are limited. In this paper we develop CondenseNet, a novel network architecture with unprecedented efficiency.
Huang, Gao   +3 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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