Results 101 to 110 of about 6,761,174 (326)
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
THE INFLUENCE OF ENVIRONMENT UPON THE BIOLOGICAL PROCESSES OF THE VARIOUS MEMBERS OF THE COLON GROUP OF BACILLI [PDF]
, 1897 Adelaide Ward Peckham
openalex +1 more source
FEBS Letters, EarlyView.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
MetalsIn this work, the evolution of mechanical properties of binary Al–Li alloys with four approximately equal gradient Li contents (0.91–3.98 wt.%) under aging conditions is thoroughly investigated.
Ganghui Li +10 more
doaj +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
The Disappearance of the Coli-aerogenes Group in Natural Purification Processes as Determined by Direct Plate Counts [PDF]
, 1933 C. C. Ruchhoft +3 more
openalex +1 more source
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
MetalsIn 6000-series Al-Mg-Si alloys, Zn is commonly added to enhance the aging response for improved properties. However, the segregation of Zn to interfaces and its interaction mechanisms with strengthening phases remain unclear.
Ying Li +9 more
doaj +1 more source
Semi-groups of isometries and the representation and multiplicity of weakly stationary stochastic processes [PDF]
, 1966 G. Kallianpur, V. Mandrekar
openalex +1 more source
, 1958 Psychology is the scientific study of the behavior of organisms, particularly the processes involved in the complex organization of these organisms as individuals.
Bloom, Robert L. +6 more
core