Results 131 to 140 of about 26,644,987 (330)

Hydrostructural and dynamic characteristics of compacted Nanning red clay considering wetting-drying impacts

open access: yesScientific Reports
Lateritic soils, also known as red soils, are prone to actions of external environment such as wetting and drying processes and their cycling. However, in the practice of pavement design in red soil regions, there lacks experimental studies and ...
Sen Deng   +7 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

On Orbits of the Ring Zmn under Action of the Group SL(m, Zn)

open access: yesActa Polytechnica, 2005
We consider the action of the finite matrix group SL(m,Zn ) on the ring Zmn. We determine orbits of this action for n arbitrary natural number. It is a generalization of the task which was studied by A. A. Kirillov for m = 2 and n prime number.
P. Novotný, J. Hrivnák
doaj  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Detecting underdetermination in parameterized quantum circuits

open access: yesMachine Learning: Science and Technology
A central question in machine learning is how reliable the predictions of a trained model are. Reliability includes the identification of instances for which a model is likely not to be trusted based on an analysis of the learning system itself.
Marie Kempkes   +3 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

System-Level Review and Advances in Axial-Flux Permanent-Magnet Machines: Topology Classification, Design Optimisation, Materials, Modelling, and Control Strategies

open access: yesApplied Sciences
Axial-flux permanent-magnet (AFPM) machines are becoming an increasingly promising solution for electromechanical systems requiring high power density. In particular, their use is expanding to electric vehicles (EVs), the aerospace industry, and advanced
Roman Tangalychev   +4 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Experimental investigations on in-plane and out-of-plane flexural performance of UHPC beams with wet joints

open access: yesFrontiers in Materials
Prefabricated bridges have emerged as a significant trend in modern bridge construction. To study the in-plane and out-of-plane flexural performance of ultra-high-performance concrete (UHPC) beams with wet joints, in-plane and out-of-plane specimens with
Shijing Chen   +5 more
doaj   +1 more source

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