Results 91 to 100 of about 23,553,376 (354)

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Melonic phase transition in group field theory

open access: yes, 2014
Group field theories have recently been shown to admit a 1/N expansion dominated by so-called `melonic graphs', dual to triangulated spheres. In this note, we deepen the analysis of this melonic sector.
Baratin, Aristide   +4 more
core   +2 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Overlap singularity and time evolution in integrable quantum field theory

open access: yesJournal of High Energy Physics, 2018
We study homogeneous quenches in integrable quantum field theory where the initial state contains zero-momentum particles. We demonstrate that the two-particle pair amplitude necessarily has a singularity at the two-particle threshold.
D. X. Horváth, M. Kormos, G. Takács
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Conformal invariance in the long-range Ising model

open access: yesNuclear Physics B, 2016
We consider the question of conformal invariance of the long-range Ising model at the critical point. The continuum description is given in terms of a nonlocal field theory, and the absence of a stress tensor invalidates all of the standard arguments for
Miguel F. Paulos   +3 more
doaj   +1 more source

Group manifold approach to higher spin theory

open access: yes, 2015
We consider the group manifold approach to higher spin theory. The deformed local higher spin transformation is realized as the diffeomorphism transformation in the group manifold $\textbf{M}$.
Hu, Shan, Li, Tianjun
core   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

On holographic entanglement entropy of Horndeski black holes

open access: yesJournal of High Energy Physics, 2017
We study entanglement entropy in a particular tensor-scalar theory: Horndeski gravity. Our goal is two-fold: investigate the Lewkowycz-Maldacena proposal for entanglement entropy in the presence of a tensor-scalar coupling and address a puzzle existing ...
Elena Caceres   +2 more
doaj   +1 more source

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