Results 101 to 110 of about 6,228,982 (277)
Invariances in Physics and Group Theory
, 2013 This is a short review of the heritage of Klein's Erlangen program in modern physics.Comment: Talk given at the Conference "Lie and Klein; the Erlangen program and its impact on mathematics and physics", Strasbourg, Sept ...
Zuber, Jean-Bernard
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Gravitational waves from a Pati-Salam phase transition
Journal of High Energy Physics, 2019 We analyse the gravitational wave and low energy signatures of a Pati-Salam phase transition. For a Pati-Salam scale of M PS ∼ 105 GeV, we find a stochastic power spectrum within reach of the next generation of ground-based interferometer experiments ...
Djuna Croon +2 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Representation Theory of Twisted Group Double
, 2003 This text collects useful results concerning the quasi-Hopf algebra $\D $. We give a review of issues related to its use in conformal theories and physical mathematics.
Altschuler, D. +2 more
core +3 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Dark kinetic heating of exoplanets and brown dwarfs
Journal of High Energy PhysicsDark kinetic heating of neutron stars has been previously studied as a promising dark matter detection avenue. Kinetic heating occurs when dark matter is sped up to relativistic speeds in the gravitational well of high-escape velocity objects, and ...
Javier F. Acevedo +2 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source