Results 131 to 140 of about 19,066,483 (360)

Brauer Theory for Profinite Groups [PDF]

open access: yesarXiv, 2013
Brauer Theory for a finite group can be viewed as a method for comparing the representations of the group in characteristic 0 with those in prime characteristic. Here we generalize much of the machinery of Brauer theory to the setting of profinite groups.
arxiv  

Covering group theory for topological groups

open access: yesTopology and its Applications, 2001
AbstractWe develop a covering group theory for a large category of “coverable” topological groups, with a generalized notion of “cover”. Coverable groups include, for example, all metrizable, connected, locally connected groups, and even many totally disconnected groups. Our covering group theory produces a categorial notion of fundamental group, which,
Conrad Plaut, Valerii N. Berestovskii
openaire   +2 more sources

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Gravitational waves from a Pati-Salam phase transition

open access: yesJournal of High Energy Physics, 2019
We analyse the gravitational wave and low energy signatures of a Pati-Salam phase transition. For a Pati-Salam scale of M PS ∼ 105 GeV, we find a stochastic power spectrum within reach of the next generation of ground-based interferometer experiments ...
Djuna Croon   +2 more
doaj   +1 more source

Group Theory Analysis to Study Phase Transitions of Quasi-2D Sr3Hf2O7. [PDF]

open access: yesNanomaterials (Basel), 2021
da Silva EL   +8 more
europepmc   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

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