Results 81 to 90 of about 897,561 (319)

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Group Theory of Syntactical Freedom in DNA Transcription and Genome Decoding. [PDF]

open access: yesCurr Issues Mol Biol, 2022
Planat M   +5 more
europepmc   +1 more source

AN APPLICATION OF GROUP THEORY [PDF]

open access: yesSchool Science and Mathematics, 1907
n ...
openaire   +2 more sources

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Electroweak baryogenesis and the standard model effective field theory

open access: yesJournal of High Energy Physics, 2018
We investigate electroweak baryogenesis within the framework of the Standard Model Effective Field Theory. The Standard Model Lagrangian is supplemented by dimension-six operators that facilitate a strong first-order electroweak phase transition and ...
Jordy de Vries   +3 more
doaj   +1 more source

Correspondences and the Theory of Groups [PDF]

open access: yesTransactions of the American Mathematical Society, 1906
The object of this paper is to bring together several points connected with the general theory of correspondences and continuous groups, and to apply them to the theory of screws. Although the several results are in general not new, it seems of interest to give the accompanying presentation of the subject, as it furnishes an excellent examiple of the ...
openaire   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

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