Results 41 to 50 of about 35,388 (266)

Understanding Dispersion of Revolver-Type Anti-Resonant Hollow Core Fibers

Fibers, 2018
Here, we analyze the dispersion behavior of revolver-type anti-resonant hollow core fibers, revealing that the chromatic dispersion of this type of fiber geometry is dominated by the resonances of the glass annuluses, whereas the actual arrangement of ...
Matthias Zeisberger, Alexander Hartung, Markus A. Schmidt   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Experimentally Validated Dispersion Tailoring in a Silicon Strip Waveguide With Alumina Thin-Film Coating

IEEE Photonics Journal, 2018
We propose a silicon strip waveguide structure with alumina thin-film coating in-between the core and the cladding for group-velocity dispersion tailoring.
Kai Guo, Jesper. B. Christensen, Xiaodong Shi, Erik. N. Christensen, Li Lin, Yunhong Ding, Haiyan Ou, Karsten Rottwitt   +7 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Confirmation of an Anomalously Low Dark Matter Content for the Galaxy NGC 1052-DF4 from Deep, High-resolution Continuum Spectroscopy

The Astrophysical Journal, 2023
NGC 1052-DF4 was found to be the second “galaxy lacking dark matter” in the NGC 1052 group, based on its velocity dispersion of ${\sigma }_{\mathrm{gc}}={4.2}_{-2.2}^{+4.4}$ km s ^−1 as measured from the radial velocities of seven of its globular ...
Zili Shen, Pieter van Dokkum, Shany Danieli   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Intermodal group velocity dispersion of few-mode fiber

IEICE Electronics Express, 2010
The intermodal dispersion of few-mode fiber limits the propagation distance of mode division multiplexing (MDM). We numerically investigate the propagation constant and group velocity of few-mode fibers. The refractive index profile of few-mode fibers should be designed to achieve long and dense MDM transmissions with digital coherent receivers.
Hirokazu Kubota, Hidehito Takara, Tadao Nakagawa, Munehiro Matsui, Toshio Morioka   +4 more
openaire   +1 more source

Kerr nonlinearity and group velocity dispersion of InGaAs/InP and GaAsSb/InP waveguides in the mid-infrared

APL Photonics, 2023
We report measurements of Kerr nonlinearity and group velocity dispersion in In0.53Ga0.47As/InP and GaAs0.51Sb0.49/InP ridge waveguides in the mid-infrared using four-wave mixing at λ ≈ 5 µm.
Kevin Zhang, Gerhard Böhm, Mikhail A. Belkin   +2 more
doaj   +1 more source

Direct surface wave tomography for three dimensional structure based on surface wave traveltimes: Methodology review and applications

地球与行星物理论评, 2023
Surface wave tomography using dispersion data to obtain isotropic and anisotropic shear wave velocity structures is a very efficient approach to study regional and global tectonics and deformation and to probe high-resolution crustal, upper mantle and ...
Huajian Yao, Song Luo, Cheng Li, Shaoqian Hu, Hongjian Fang   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source