Results 71 to 80 of about 40,507 (308)

The anelastic structure and deep geology of the Derbyshire Dome from high frequency Rayleigh waves. [PDF]

open access: yes, 1984
This work is an investigation of the anelastic structure of the Derbyshire Dome and adjacent areas from the analysis of high frequency, 0.6 - 4.2 Hz, fundamental mode Rayleigh waves observed from quarry blasts within the study area.
McDonald, Andrew James William
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Femtosecond filamentation of optical vortex in a medium with anomalous group velocity dispersion

open access: yesEPJ Web of Conferences, 2017
Within the framework of the slowly varying wave approximation method, the pictures of spatio-temporal dynamics of femtosecond pulse in a ring beam with phase singularity were obtained during propagation in CaF2 crystal with anomalous group velocity ...
Vasilyev Evgeny   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Inviscid mean flow through and around groups of bodies

open access: yes, 2004
General estimates are derived for mean velocities through and around groups or arrays of fixed and moving bodies, in unbounded and bounded domains, which lie within a defined perimeter.
Hunt, J. C. R.   +13 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

V-Waves: Spatio-temporally induced group-velocity dispersion in free space

open access: yes, 2021
Introducing precise spatio-temporal structure into a pulsed optical field can lead to remarkable changes with its free propagation. `Space-time' (ST) wave packets, for example, propagate rigidly at a tunable group velocity in free space by inculcating a ...
Layton A. Hall (14340729)   +1 more
core   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

Electron Scattering via Interface Optical Phonons with High Group Velocity in Wurtzite GaN-based Quantum Well Heterostructure

open access: yesScientific Reports, 2018
Here we present a detailed theoretical analysis of the interaction between electrons and optical phonons of interface and confined modes in a wurtzite AlN/GaN/AlN quantum well heterostructure based on the uniaxial dielectric continuum model.
Kihoon Park   +4 more
doaj   +1 more source

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