Results 121 to 130 of about 10,981,188 (298)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Exponent growth in groups acting on regular rooted trees [PDF]

open access: yes
openWhenever G is a group acting on a regular rooted tree, it is possible to define a canonical chain {Ni} of finite-index normal subgroups of G, which take the name of level stabilizers in G.
MAINI, ELENA
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Algorithms for polycyclic-by-finite groups [PDF]

open access: yes
A set of fundamental algorithms for computing with polycyclic-by-finite groups is presented here. Polycyclic-by-finite groups arise naturally in a number of contexts; for example, as automorphism groups of large finite soluble groups, as quotients of ...
Sinanan, Shavak
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Galaxy Group Ellipticity Confirms a Younger Cosmos

open access: yesUniverse
We present an analysis of the ellipticities of galaxy groups, derived from the spatial distribution of member galaxies, revealing a notable incongruity between the observed local galaxy groups and their counterparts in the Lambda cold dark matter ...
Yu Rong
doaj   +1 more source

The Multiplication Group of an AG-group

open access: yes, 2014
We investigate the multiplication group of a special class of quasigroup called AG-group. We prove some interesting results such as: the multiplication group of an AG-group of order n is non-abelian group of order 2n and its left section is an abelian group of order n. The inner mapping group of an AG-group of any order is a cyclic group of order 2.
Shah, M., Ali, A., Ahmad, I., Sorge, V.
openaire   +3 more sources

The connective K theory of semidihedral groups [PDF]

open access: yes, 2010
The real connective K-homology of finite groups ko¤(BG), plays a big role in the Gromov-Lawson-Rosenberg (GLR) conjecture. In order to compute them, we can calculate complex connective K-cohomology, ku¤(BG), first and then follow by computing complex ...
Rodtes, Kijti
core  

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