Results 131 to 140 of about 10,981,188 (298)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Relatively hyperbolic groups are C*-simple
, 2006 We characterize relatively hyperbolic groups whose reduced C*-algebra is simple as those, which have no non-trivial finite normal ...
Arzhantseva, G. +5 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Forum: Qualitative Social Research, 2002 In two projects at the University of Heidelberg we tested the video analysis software THEME (MAGNUSSON, 1997) in order to identify communicative patterns in task-oriented small group interaction.
Sabine C. Koch, Jörg Zumbach
doaj
We develop a general theory for asymptotically CAT(0) groups; these are groups acting geometrically on a geodesic space, all of whose asymptotic cones are CAT(0)
Kar, Aditi
core
Ends of groups : a computational approach [PDF]
We develop ways in which we can find the number of ends of automatic groups and groups with solvable word problem. In chapter 1, we provide an introduction to ends, splittings, and computa- tion in groups. We also remark that the `JSJ problem'
Clow, Andrew David Menzies
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Asian business groups : context, governance and performance /
, 2008 The Asian economic landscape is dominated by various types of business group. Asian Business Groups provides a comprehensive review and introduction to the different types of business group.
Carney, Michael.
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source