Results 191 to 200 of about 5,873,812 (294)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Effect of Vertebral Body Tether Tensioning on Vertebral Body Growth Modulation. [PDF]

JOR Spine
Jackson TJ, Louer C, El-Hawary R, Hurry J, Nian H, Farnsworth C, Bartley CE, Bryan TP, Kelly MP, Newton PO, Parent S, Pediatric Spine Study Group, Upasani VV.   +12 more
europepmc   +1 more source

The Growth of Rats upon Diets of Isolated Food Substances [PDF]

, 1916
Thomas B. Osborne, Lafayette B. Mendel
openalex   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Climate-driven physiological changes in Mahseer (Tor tambroides) juveniles. [PDF]

Sci Rep
Iskandar NS, Noor NM, Cob ZC, Das SK, Abdullah MAA.   +4 more
europepmc   +1 more source

EVIDENCE FOR THE ESSENTIALITY OF SILICON FOR GROWTH OF THE BEET PLANT [PDF]

, 1939
G. J. Raleigh
openalex   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Reduction in Earth's carbon budget imbalance. [PDF]

Nat Commun
Pandey S, Chevallier F, Rödenbeck C, Byrne B, Chatterjee A, Liu J, Frankenberg C.   +6 more
europepmc   +1 more source

The Growth of Great Cities in Area and Population

, 1899
Edmund J. James
openalex   +2 more sources

A Comparative Study of Tumour and Normal Tissue Growth [PDF]

, 1917
J. C. Drummond
openalex   +1 more source