Results 141 to 150 of about 1,653,692 (278)

Mapeamento de QTL para características de crescimento de suínos por meio de modelos de regressão aleatória QTL mapping for growth traits of pigs using random regression models

open access: yesPesquisa Agropecuária Brasileira, 2013
O objetivo deste trabalho foi avaliar eficiência de modelos de regressão aleatória (MRA) para detectar locus de características quantitativas (QTL) para características de crescimento, em suínos.
Valeria Rosado Pinheiro   +6 more
doaj  

Childhood waist growth curves and adult diabetes. [PDF]

open access: yesJ Dev Orig Health Dis, 2022
Carli MM, Sabo RT, Sun SS.
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Growth Curves of Chinese Children with Androgen Insensitivity Syndrome: A Multicenter Registry Study. [PDF]

open access: yesJ Pers Med, 2022
Zhao X   +12 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Growth Curve of Infants [PDF]

open access: yesProceedings of the National Academy of Sciences, 1936
C B, Davenport, W, Drager
openaire   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Understanding orthopedic infections through a different perspective: Microcalorimetry growth curves. [PDF]

open access: yesExp Ther Med, 2022
Popa M   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy