Results 131 to 140 of about 898,691 (302)

Maternal anxiety and depression in the context of suspected infant food allergy: A prospective cohort study on trajectories and predictors

Allergy Medicine
Background: The period of suspected infant food allergy places a significant psychological burden on mothers. However, the key drivers of their long-term emotional trajectories remain unclear.
Jun Fang, Rui'an Wang, Zhanzhan Zhang, Yuanfeng Zhong, Yannan Wan, Qian Chen, Xuelin Xia, Xuan Zhang   +7 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Disorder of Differential Growth [PDF]

BMJ, 1966
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Editorial: Novel Insights Into the Genetics of Growth Disorders. [PDF]

Front Genet, 2022
Giordano M, Stuppia L.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Psychotic Disorders and Posttraumatic Growth [PDF]

Posttraumatic growth (PTG) represents the phenomenon of positive changes that a person can experience after a traumatic experience. Traditionally associated with traumatic events such as loss or injury, PTG is increasingly being investigated in people ...
Damašek, Igor, Delalle, Mirela, Pavličević Tomas, Ivana, Čavajda, Zoran, Erić, Ivan, Petek Erić, Anamarija   +5 more
core   +1 more source

Is There a Correlation between Apelin and Insulin Concentrations in Early Second Trimester Amniotic Fluid with Fetal Growth Disorders? [PDF]

J Clin Med, 2023
Vrachnis D, Antonakopoulos N, Fotiou A, Pergialiotis V, Loukas N, Valsamakis G, Iavazzo C, Stavros S, Maroudias G, Panagopoulos P, Vlahos N, Peppa M, Stefos T, Mastorakos G.   +13 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Accelerating digital health literacy for the treatment of growth disorders: The impact of a massive open online course. [PDF]

Front Public Health, 2023
Dimitri P, Fernandez-Luque L, Koledova E, Malwade S, Syed-Abdul S.   +4 more
europepmc   +1 more source