Convergent DNA methylation abnormalities at enhancers and bivalent promoters in human growth disorders. [PDF]
Wheeler MES +12 more
europepmc +1 more source
Identifying fetal growth disorders using ultrasound in obese nulliparous women. [PDF]
Dude AM, Davis B, Delaney K, Yee LM.
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Placental expression and activity of system A and system L amino acid transporters in pregnancies complicated by diabetes mellitus and fetal growth disorders: a systematic review. [PDF]
Ługowski F +3 more
europepmc +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Automated bone age assessment in rare pediatric growth disorders: a comparative study using Deeplasia. [PDF]
Skaf K +11 more
europepmc +1 more source
Imaging of pediatric bone and growth disorders: Of diagnostic workhorses and new horizons. [PDF]
Mehany SN, Patsch JM.
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Indirect exposure to organophosphate pesticides and its possible growth disorders in children of farmers in Northwest Mexico. [PDF]
Ochoa-Ruiz E +10 more
europepmc +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source

