Results 181 to 190 of about 10,050,077 (365)

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Disorders of Growth

Medicine, 2001
Tim J Cole, Peter C. Hindmarsh
openaire   +2 more sources

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

The Disorders of Post-natal Growth and Development

, 1911
H. Gilford
openalex   +2 more sources

Obliterative bronchiolitis after lung transplantation: a fibroproliferative disorder associated with platelet-derived growth factor. [PDF]

, 1992
Marshall I. Hertz, Craig A. Henke, Raouf E. Nakhleh, Keith R. Harmon, William A. Marinelli, J. M. K. Fox, S H Kubo, Sara J. Shumway, R. Morton Bolman, Peter B. Bitterman   +9 more
openalex   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Fetal alcohol spectrum disorders

Nature Reviews Disease Primers, 2023
Svetlana Popova, M. E. Charness, Larry Burd, Andi Crawford, H. Hoyme, Raja Mukherjee, Edward P. Riley, Elizabeth J Elliott   +7 more
semanticscholar   +1 more source

The Status of Young Children\'s Nutrition Security in Rural Area of Northwest Ethiopia [PDF]

Journal of Nutrition and Food Security
Background: Nutrition security is a vital component of growth and development in a nation. However, dietary diversity and availability of healthy food are serious challenges to many local communities in Ethiopia.
Fentaw Teshome, Adino Andaregie, Tessema Astatkie, Beneberu Assefa   +3 more
doaj  

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Serum Growth Hormone Levels Measured by Radioimmunoassay and Radioreceptor Assay: A Useful Diagnostic Tool in Children with Growth Disorders?* [PDF]

, 1990
M.M. Ilondo, M Vanderschueren‐Lodeweyckx, Pierre De Meyts, E. Eggermont   +3 more
openalex   +1 more source