Results 181 to 190 of about 10,595,923 (382)

Mapping the Functional Epitopes of Human Growth Hormone: Integrating Structural and Evolutionary Data with Clinical Variants

Current Issues in Molecular Biology
Human growth hormone (GH) exerts its pleiotropic effects by binding to its receptor (GHR), leading to receptor dimerization and activation. We combined structural, evolutionary, and genetic analyses to elucidate the critical determinants of GH-GHR ...
Sonia Verma, Amit V. Pandey
doaj   +1 more source

Factors Associated with Psychiatric Morbidity, Post-Traumatic Stress Disorder and Post-Traumatic Growth in Paramedic First Responders: The Role of Core Beliefs

, 2020
Lois J. Surgenor, Deborah L. Snell, Martin J. Dorahy   +2 more
openalex   +2 more sources

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Protein disorder–order interplay to guide the growth of hierarchical mineralized structures [PDF]

, 2018
Sherif Elsharkawy, Maisoon Al‐Jawad, Maria F. Pantano, Esther Tejeda‐Montes, Khushbu Mehta, Hasan Jamal, Shweta Agarwal, Kseniya Shuturminska, Alistair Rice, Nadezda V. Tarakina, Rory M. Wilson, A. J. Bushby, Matilde Alonso, José Carlos Rodríguez‐Cabello, Ettore Barbieri, Armando E. del Río Hernández, Molly M. Stevens, Nicola M. Pugno, Paul Anderson, Álvaro Mata   +19 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Altered serum levels of vascular endothelial growth factor and glial-derived neurotrophic factor but not fibroblast growth factor-2 in treatment-naive children with attention deficit/hyperactivity disorder

, 2019
Nihal Yurteri, İbrahim Şahin, Ali Evren Tufan   +2 more
openalex   +2 more sources

Comparative Evaluation and Co-relation of Difficult Airway and Temporomandibular Joint Disorder in Skeletal Class II Vertical Growth Pattern and Class-I Malocclusion – An Observational Study

, 2021
Shruti Rathi, Rizwan Gilani
openalex   +2 more sources

Intrauterine Growth Restriction Induces Adulthood Chronic Metabolic Disorder in Cardiac and Skeletal Muscles [PDF]

, 2022
Ping Li, Lewei He, Yue Lan, Jie Fang, Zhenxin Fan, Yifei Li   +5 more
openalex   +1 more source

Human growth disorders associated with impaired GH action: Defects in STAT5B and JAK2. [PDF]

Mol Cell Endocrinol, 2021
Hwa V.
europepmc   +1 more source