Results 131 to 140 of about 18,735,403 (324)

Effects of chitosan nanoparticles on growth, development, and nutraceutical quality of tomato (Solanum lycopersicum L.)

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca
The tomato (Solanum lycopersicum L.), considered one of the most desirable horticultural crops in the world for its nutritional and nutraceutical qualities, is also used as a model for many studies.
Juan J. REYES-PÉREZ   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Differences in Vegetative, Productive, and Physiological Behaviors in Actinidia chinensis Plants, cv. Gold 3, as A Function of Cane Type

open access: yesPlants
This study investigated the influence of cane diameter on vegetative, productive, and physiological behaviors in Actinidia chinensis, cv. Gold 3. Conducted over two years (2021–2022), the experiment compared canes with larger (HD) and smaller (LD ...
Gregorio Gullo   +6 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Novel Quantitative Assessment Pipeline of Organoid Growth Dynamics Using Adapted Light Absorption and Surface Area Normalization Models

open access: yesAdvanced NanoBiomed Research
2D characterization of organoids by light microscopy with live cell imaging systems provides a powerful, rapid approach toward characterizing organoid growth patterns and behavior under different conditions with high temporal resolution. However, current
Woojin Yang   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Quantitative anatomy of the infraspinatus muscle in the human foetus

open access: yesFolia Morphologica
BACKGROUND: The study presents one of the 6 scapulohumeral muscles, which occupies most of the osteofibrous infraspinatus compartment. Along with the supraspinatus, teres minor, and subscapularis muscles, the infraspinatus muscle contributes to the ...
Maciej Biernacki   +5 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

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