Results 111 to 120 of about 17,056,935 (242)
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
FACTORS NECESSARY FOR MAXIMUM GROWTH OF CLOSTRIDIUM BIFERMENTANS [PDF]
Louis DeSpain Smith, Howard C. Douglas
openalex +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Factors influencing yield, color, size and growth in apples ...
John Pogue Stewart
openalex +2 more sources
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Further Information Concerning Unidentified Chick Growth Factors
A.A. Camp+3 more
openalex +1 more source
Probable Identity of Unidentified Chick Growth Factors in Fish Solubles and Penicillin Mycelium Residue [PDF]
H.M. Edwards+3 more
openalex +1 more source
Transforming growth factor-beta induces development of the T(H)17 lineage.
Paul R. Mangan+9 more
semanticscholar +1 more source