Results 111 to 120 of about 6,589,084 (383)
Growth and Differentiation Factors [PDF]
ABSTRACTThis review is restricted to neutrophilic granulocytes (granulocytes), monocytes (macrophages), and eosinophils, with only passing reference to cells that are also usually included in the “myeloid” category—megakaryocytes, mast cells, and erythroid cells. Although some dendritic cells are of myeloid origin, they are discussed elsewhere.
openaire +2 more sources
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Transient growth calculations obtained directly from the Orr-Sommerfeld matrices [PDF]
We introduce and validate an algorithm to compute transient amplication factors for the Orr-Sommerfeld-Squire linear theory for parallel two-phase flow. We further introduce direct numerical simulation as a way of comparing the linear theory with early-stage wave growth in simulations.
arxiv
Regulation of integrin and growth factor signaling in biomaterials for osteodifferentiation
Stem cells respond to the microenvironment (niche) they are located in. Under natural conditions, the extracellular matrix (ECM) is the essential component the in stem cell niche, in which both integrin ligands and growth factors are important regulators
Qiang Wei+4 more
doaj +1 more source
A first-in-human, phase 1, double blind, placebo-controlled, single ascending dose study examined the safety, tolerability, and exploratory efficacy of intravenous infusion of a recombinant growth factor, cimaglermin alfa, in patients with heart failure ...
Daniel J. Lenihan, MD+12 more
doaj +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
On the theoretical prediction of microalgae growth for parallel flow [PDF]
The established microalgae growth models are semi-empirical or considerable fitting coefficients exist currently. Therefore, the ability of the model prediction is reduced by the numerous fitting coefficients. Furthermore, the predicted results of the established models are dependent on the size of the photobioreactor (PBR), light intensity, flow and ...
arxiv
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever+1 more
wiley +1 more source
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source