Results 291 to 300 of about 7,029,797 (363)

Placental growth factor before 11 weeks for screening of preterm preeclampsia: The PreMoM study. [PDF]

Acta Obstet Gynecol Scand
López Mármol R, Ávila Cabreja JA, de Haro Romero T, de Paco Matallana C, Ocón Hernández O, González-Vanegas O, Carretero Lucena P, Carrillo MP, Delgado JL, Rolle V, Gormus U, Oraha L, Gil MM, Molina FS.   +13 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Diverse Biological Processes Contribute to Transforming Growth Factor β-Mediated Cancer Drug Resistance. [PDF]

Cells
Heiserman JP, Akhurst RJ.
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Update Prognostic Potency of Vascular Endothelial Growth Factor-A in the Acute Lymphoblastic Leukemia Landscape: A Meta-Analysis. [PDF]

Cancer Rep (Hoboken)
Aghaei M, JalaliFar MA, Yousefi-Avarvand A, Bahreiny SS, Karamali N, Mansouri Z, Amraei M, Alizadeh S, Saki N, Bastani MN, Sakhavarz T, Khaksar MA, Goudarzimehr L, Mousavei S, Babadi E.   +14 more
europepmc   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

From neuromodulation to bone homeostasis: therapeutic targets of nerve growth factor in skeletal diseases. [PDF]

Front Pharmacol
Chen K, Chen L, Ma Y, Chen S, Liu J, Zhou H, Chen Y, Liu G.   +7 more
europepmc   +1 more source

Functional expression and secretion of basic fibroblast growth factor in <i>Lactococcus lactis</i>. [PDF]

Front Bioeng Biotechnol
Ho PL, Chua YF, Quek JP, Ng SK, Wong FT, Ow DS.   +5 more
europepmc   +1 more source