Results 81 to 90 of about 7,216,417 (314)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Growth with a Fixed Factor [PDF]

open access: yes
Consider an economy in which a fi…xed supply of unskilled labor can be combined with knowledge capital to produce consumption. The technology for accumulating knowledge capital is linear in knowledge capital.
Erzo G. J. Luttmer
core  

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature

open access: yesClinical, Cosmetic and Investigational Dermatology, 2016
Caroline Aldag,1,* Diana Nogueira Teixeira,1,* Phillip S Leventhal2 1Merz Pharmaceuticals GmbH, Frankfurt am Main, Germany; 24Clinics, Paris, France *These authors contributed equally to this work Abstract: Skin aging is primarily due to alterations in ...
Aldag C   +2 more
doaj  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Glycosaminoglycans: Sweet as Sugar Targets for Topical Skin Anti-Aging

open access: yesClinical, Cosmetic and Investigational Dermatology, 2021
Siew Tein Wang, Boon Hoe Neo, Richard J Betts L’Oréal Research & Innovation, L’Oréal Singapore, SingaporeCorrespondence: Richard J Betts Email richard.betts@rd.loreal.comAbstract: Glycosaminoglycans (GAGs) are long, linear polysaccharides comprised of ...
Wang ST, Neo BH, Betts RJ
doaj  

Heterochrony as Diachronically Modified Cell-Cell Interactions

open access: yesBiology, 2016
Heterochrony is an enabling concept in evolution theory that metaphorically captures the mechanism of biologic change due to mechanisms of growth and development.
John S. Torday
doaj   +1 more source

Growth factor in f(T) gravity

open access: yes, 2011
We derive the evolution equation of growth factor for the matter over-dense perturbation in $f(T)$ gravity. For instance, we investigate its behavior in power law model at small redshift and compare it to the prediction of $\Lambda$CDM and dark energy ...
A.A. Starobinsky   +19 more
core   +1 more source

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