Update on HER-2 as a target for cancer therapy: alternative strategies for targeting the epidermal growth factor system in cancer [PDF]
The epidermal growth factor (EGF) family of ligands and receptors interact to influence cell division, differentiation and motility. Much evidence supports their importance in causing and sustaining cell transformation in model systems and in human ...
Gullick, William J.
core +1 more source
S.133-137GaN crystals grown from solution and vapor phase show pronounced facetting. In order to explain the occurrence of the facets, Jackson's alpha-factor is determined for the III-nitrides under various growth conditions.
Friedrich, J. +6 more
core +1 more source
High-temperature water stress corrosion cracking has high tensile stress sensitivity, and its growth rate has been evaluated using the stress intensity factor, which is a linear fracture mechanics parameter.
Tetsuo YASUOKA +2 more
doaj +1 more source
Lead (Pb) is a biologically non-essential element in the soil that brutally affects plants and other living organisms in soil; hence, its removal has become a worldwide concern.
Muhammad Rizwan Aslam +15 more
doaj +1 more source
Immunological studies of chronic ocular toxoplasmosis : up-regulation of major histocompatibility complex class I and transforming growth factor beta and a protective role for interleukin-6 [PDF]
A murine model was used to characterize the local immune and inflammatory response during ocular toxoplasmosis. Major histocompatibility complex (MHC) class I, normally expressed at low levels in immune-privileged sites such as the eye, was up-regulated ...
Byrne, N. +6 more
core +3 more sources
Role of fibroblast growth factor 8 in growth and progression of hormonal cancer
Hormonal cancers such as breast and prostate cancer arise from steroid hormone-regulated tissues. In addition to breast and prostate cancer hormonal regulation has also a role in endometrial, ovarian, testis and thyroid carcinomas.
Härkönen, Pirkko, +2 more
core +2 more sources
The mitogenic potential of heparin-binding epidermal growth factor in the human endometrium is mediated by the epidermal growth factor receptor and is modulated by tumor necrosis factor-alpha [PDF]
Heparin-binding epidermal growth factor (HB-EGF), a member of the epidermal growth factor (EGF) family, is implicated in a variety of biological processes, including reproduction.
Mardon, Helen J. +23 more
core +1 more source
Compartmentalisation-based design automation method for power grid
Power grid design and maintenance are conducted to solve the problems caused by load growth over time and to stay within the constraints of voltage drop, power factor, etc. Typically, solutions to these problems are optimised individually.
Korosh Vatanparvar +3 more
doaj +1 more source
Progressive Freeze Concentration for Leachate Treatment using Vertical Finned Crystallizer
Landfill leachate brings serious threats to public health and the environment due to its complex composition and difficult degradation. With the growing landfill leachate produced, potential pollution would be a big cause for concern.
Tazien Rashid +6 more
doaj +1 more source
Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells. [PDF]
Recent data implicate elevated transforming growth factor-β (TGFβ) signalling in BRAF inhibitor drug-resistance mechanisms, but the potential for targeting TGFβ signalling in cases of advanced melanoma has not been investigated.
Vincent, D F +85 more
core +1 more source

