Once thought to be present only in liver, muscle and adipose tissue, the GH receptor is now known to be ubiquitously distributed, in accord with the many pleiotropic actions of GH. These include the regulation of metabolism, postnatal growth, cognition, immune, cardiac and renal systems and gut function.
M. Waters
semanticscholar +6 more sources
Growth Hormone-Releasing Hormone in Diabetes [PDF]
Frontiers in Endocrinology, 2016Growth hormone-releasing hormone (GHRH) is produced by the hypothalamus and stimulates growth hormone synthesis and release in the anterior pituitary gland.
Leonid Evsey Fridlyand+3 more
doaj +4 more sources
Comparison of growth hormone stimulation tests in prepubertal children with short stature according to response to growth hormone replacement [PDF]
Annals of Pediatric Endocrinology & MetabolismPurpose Growth hormone (GH) stimulation tests are essential tools for diagnosing GH deficiency (GHD). We aimed to compare L-dopa, insulin, and arginine-induced stimulation tests based on response to GH replacement.
Seong Hwan Chang, Chan Jong Kim
doaj +2 more sources
Discontinuation of long-term growth hormone treatment in adults with growth hormone deficiency: a survey of UK practice [PDF]
Endocrine ConnectionsObjective: We conducted a survey of UK endocrine clinicians between June 2022 and August 2022 to understand current practices regarding GH treatment discontinuation in adults with growth hormone deficiency.
Sherwin Criseno+5 more
doaj +2 more sources
Response to growth hormone according to provocation test results in idiopathic short stature and idiopathic growth hormone deficiency [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2022Purpose To investigate growth response in children with either idiopathic short stature (ISS) or growth hormone (GH) deficiency (GHD). Methods The data of prepubertal GHD or ISS children treated using recombinant human GH were obtained from the LG Growth
Ju Young Yoon+9 more
doaj +1 more source
Molecular Basis for Hypochondroplasia in Japan
Endocrines, 2022Hypochondroplasia is an autosomal dominant genetic disorder due to a heterozygous pathogenic variant of the FGFR3 gene. The early diagnosis of hypochondroplasia is necessary, since growth hormone is effective for improving adult height.
Tomohiro Ishii+8 more
doaj +1 more source
Objective: Klinefelter syndrome (KS) is the most common sex chromosome disorder and genetic cause of infertility in males. A highly variable phenotype contributes to the fact that a large proportion of cases are never diagnosed.
Andre Madsen+2 more
doaj +1 more source
Growth hormone releasing hormone or growth hormone treatment in growth hormone insufficiency? [PDF]
Archives of Disease in Childhood, 1988Sixteen prepubertal children who were insufficient for growth hormone were treated with growth hormone releasing hormone (GHRH) 1-40 and GHRH 1-29 for a mean time of nine months (range 6-12 months) with each peptide. Eleven children received GHRH 1-40 in four subcutaneous nocturnal pulses (dose 4-8 micrograms/kg/day) and eight (three of whom were also ...
P J Smith, C G Brook
openaire +3 more sources
Growth hormone treatment in non-growth hormone-deficient children [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2014Until 1985 growth hormone (GH) was obtained from pituitary extracts, and was available in limited amounts only to treat severe growth hormone deficiency (GHD).
Sandro Loche+3 more
doaj +1 more source
An improved strategy to analyse strigolactones in complex sample matrices using UHPLC–MS/MS
Plant Methods, 2020Background Strigolactones represent the most recently described group of plant hormones involved in many aspects of plant growth regulation. Simultaneously, root exuded strigolactones mediate rhizosphere signaling towards beneficial arbuscular ...
Kristýna Floková+6 more
doaj +1 more source