Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient Little mice [PDF]
Clinics, 2012 OBJECTIVE: To investigate a possible direct, growth hormone-releasing, hormone-independent action of a growth hormone secretagogue, GHRP-2, in pituitary somatotroph cells in the presence of inactive growth hormonereleasing hormone receptors.
Cibele N. Peroni +7 more
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Novel mechanisms of growth hormone regulation: growth hormone-releasing peptides and ghrelin [PDF]
Brazilian Journal of Medical and Biological Research, 2006 Growth hormone secretion is classically modulated by two hypothalamic hormones, growth hormone-releasing hormone and somatostatin. A third pathway was proposed in the last decade, which involves the growth hormone secretagogues.
A.-M.J. Lengyel
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Growth Hormone-Releasing Hormone in Diabetes [PDF]
Frontiers in Endocrinology, 2016 Growth hormone-releasing hormone (GHRH) is produced by the hypothalamus and stimulates growth hormone synthesis and release in the anterior pituitary gland.
Leonid Evsey Fridlyand +3 more
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Efficacy in Japanese adults with growth hormone deficiency receiving weekly somapacitan or daily growth hormone: results from phase 3 REAL 1 trial [PDF]
Frontiers in EndocrinologyIntroductionSomapacitan is a long-acting growth hormone (GH) derivative approved for once-weekly treatment of adult GH deficiency (AGHD). This study aimed to evaluate the efficacy and safety of somapacitan and daily GH in Japanese individuals with AGHD ...
Fumio Otsuka +5 more
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On the plant growth hormone produced by Rhizopus suinus [PDF]
, 1935 Since it was first discovered that cell elongation in the Avena coleoptile is controlled by a hormone, our understanding of the nature and rôle of this substance has progressed considerably. Apart from the elucidation of its functions in promoting growth,
Thimann, Kenneth V.
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Comparison of growth hormone stimulation tests in prepubertal children with short stature according to response to growth hormone replacement [PDF]
Annals of Pediatric Endocrinology & MetabolismPurpose Growth hormone (GH) stimulation tests are essential tools for diagnosing GH deficiency (GHD). We aimed to compare L-dopa, insulin, and arginine-induced stimulation tests based on response to GH replacement.
Seong Hwan Chang, Chan Jong Kim
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Response to growth hormone according to provocation test results in idiopathic short stature and idiopathic growth hormone deficiency [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2022 Purpose To investigate growth response in children with either idiopathic short stature (ISS) or growth hormone (GH) deficiency (GHD). Methods The data of prepubertal GHD or ISS children treated using recombinant human GH were obtained from the LG Growth
Ju Young Yoon +9 more
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Molecular Basis for Hypochondroplasia in Japan
Endocrines, 2022 Hypochondroplasia is an autosomal dominant genetic disorder due to a heterozygous pathogenic variant of the FGFR3 gene. The early diagnosis of hypochondroplasia is necessary, since growth hormone is effective for improving adult height.
Tomohiro Ishii +8 more
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Endocrine Connections, 2023 Objective: Klinefelter syndrome (KS) is the most common sex chromosome disorder and genetic cause of infertility in males. A highly variable phenotype contributes to the fact that a large proportion of cases are never diagnosed.
Andre Madsen +2 more
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Growth hormone releasing hormone or growth hormone treatment in growth hormone insufficiency? [PDF]
Archives of Disease in Childhood, 1988 Sixteen prepubertal children who were insufficient for growth hormone were treated with growth hormone releasing hormone (GHRH) 1-40 and GHRH 1-29 for a mean time of nine months (range 6-12 months) with each peptide. Eleven children received GHRH 1-40 in four subcutaneous nocturnal pulses (dose 4-8 micrograms/kg/day) and eight (three of whom were also ...
P J Smith, C G Brook
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