Results 1 to 10 of about 562,443 (311)
Efficacy in Japanese adults with growth hormone deficiency receiving weekly somapacitan or daily growth hormone: results from phase 3 REAL 1 trial [PDF]
Frontiers in EndocrinologyIntroductionSomapacitan is a long-acting growth hormone (GH) derivative approved for once-weekly treatment of adult GH deficiency (AGHD). This study aimed to evaluate the efficacy and safety of somapacitan and daily GH in Japanese individuals with AGHD ...
Fumio Otsuka +5 more
doaj +2 more sources
Response to growth hormone according to provocation test results in idiopathic short stature and idiopathic growth hormone deficiency [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2022 Purpose To investigate growth response in children with either idiopathic short stature (ISS) or growth hormone (GH) deficiency (GHD). Methods The data of prepubertal GHD or ISS children treated using recombinant human GH were obtained from the LG Growth
Ju Young Yoon +9 more
doaj +1 more source
Molecular Basis for Hypochondroplasia in Japan
Endocrines, 2022 Hypochondroplasia is an autosomal dominant genetic disorder due to a heterozygous pathogenic variant of the FGFR3 gene. The early diagnosis of hypochondroplasia is necessary, since growth hormone is effective for improving adult height.
Tomohiro Ishii +8 more
doaj +1 more source
Endocrine Connections, 2023 Objective: Klinefelter syndrome (KS) is the most common sex chromosome disorder and genetic cause of infertility in males. A highly variable phenotype contributes to the fact that a large proportion of cases are never diagnosed.
Andre Madsen +2 more
doaj +1 more source
Growth hormone treatment in non-growth hormone-deficient children [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2014 Until 1985 growth hormone (GH) was obtained from pituitary extracts, and was available in limited amounts only to treat severe growth hormone deficiency (GHD).
Sandro Loche +3 more
doaj +1 more source
An improved strategy to analyse strigolactones in complex sample matrices using UHPLC–MS/MS
Plant Methods, 2020 Background Strigolactones represent the most recently described group of plant hormones involved in many aspects of plant growth regulation. Simultaneously, root exuded strigolactones mediate rhizosphere signaling towards beneficial arbuscular ...
Kristýna Floková +6 more
doaj +1 more source
Effects of zearalenone on ovarian development of prepubertal gilts through growth hormone axis
Frontiers in Veterinary Science, 2022 This experiment aimed to establish the effects of zearalenone (ZEN) on ovarian development in prepubertal gilts through the growth hormone axis [growth hormone-releasing hormone (GHRH) / growth hormone (GH) / growth hormone receptor (GHR)].
Fengyang Wu +8 more
doaj +1 more source
Endocrines, 2022 Short stature is a common reason for a child to visit the endocrinologist, and can be a variant of normal or secondary to an underlying pathologic cause. Pathologic causes include growth hormone deficiency (GHD), which can be congenital or acquired later.
Colleen O'Neill +2 more
doaj +1 more source
Vitamin D and Parathyroid Hormone during Growth Hormone Treatment
Children, 2022 Background. There is some controversy concerning a potential interaction between vitamin D and PTH and the GH/IGF-1 axis. The goal of this study is to assess vitamin D and PTH status in children with GH deficiency at diagnostic and during treatment with ...
Teodoro Durá-Travé +1 more
doaj +1 more source
Trends in Pediatrics, 2021 Objective: A small number of studies were reported regarding the direct and indirect effects of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) especially on the erythrocyte series. The purpose of this study was to examine the effects of GH
Derya Şengün, Atilla Çayır
doaj +1 more source