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Growth hormone response to growth hormone-releasing hormone and clonidine in depression
Biological Psychiatry, 1995Growth hormone (GH) responses to the alpha 2-adrenoceptor agonist clonidine and to GH-releasing hormone (GHRH) were measured in 12 patients fulfilling DSM-III-R criteria for major depressive disorder and in 12 age- and sex-matched controls. GH responses to clonidine correlated significantly with the GH responses to GHRH in the depressed patients as ...
Gann, Horst J. +4 more
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Growth Hormone-Releasing Hormone and Growth Hormone Secretagogues in Normal Aging
Endocrine, 2003Growth hormone (GH) secretion declines with aging, and parallels between normal aging and the signs and symptoms of adult GH deficiency have led to interest in the potential utility of replacing or stimulating GH to promote physical and psychological function and to prolong the capacity for independent living in older adults.
George R. Merriam +3 more
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Sex differences in growth hormone response to growth hormone-releasing hormone
Journal of Endocrinological Investigation, 1991The aim of the present study was to ascertain whether sex differences exist in GH response to GHRH, and the influence that menstrual cycle have on this response. A GHRH test was performed on nine healthy men and ten women on days one and twelve of the menstrual cycle.
Lucinda Cacicedo +5 more
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Growth Hormone Responses to Continuous Infusions of Growth Hormone-Releasing Hormone*
The Journal of Clinical Endocrinology & Metabolism, 1985The pattern of GH secretion during a continuous 4-h iv infusion of 1 microgram/kg.h GH-releasing hormone (1-44)-NH2 (GHRH-44) or saline was examined in 15 adult men. There was prompt release of GH beginning within 20 min of starting the GHRH-44 infusions, reaching peak GH levels of 43 +/- 11 (+/- SE) ng/ml within 60-90 min.
D. Lynn Loriaux +7 more
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Growth hormone response to growth hormone-releasing hormone in schizophrenic patients
American Journal of Psychiatry, 1990Ten schizophrenic patients and five normal control subjects were challenged with growth hormone-releasing hormone in a pilot study investigating growth hormone secretion from the pituitary. The results suggest suprapituitary dysfunction in schizophrenia, but replication in a larger study is needed.
J.A. Lieberman +4 more
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Growth hormone response to growth hormone releasing hormone in depression and schizophrenia
Psychiatry Research, 1990Growth hormone releasing hormone, a 44-amino acid peptide (GHRH-44), was administered (1 micrograms/kg i.v.) to 6 normal controls, 10 schizophrenic subjects, and 7 depressed subjects. A significantly lower growth hormone (GH) response was found in the schizophrenic and depressed groups.
Edith Markoff +5 more
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Reviews in Endocrine and Metabolic Disorders, 1998
Growth hormone (GH) actions impact growth, metabolism, and body composition and have been associated with aging and longevity. Lack of GH results in slower growth, delayed maturation, and reduced body size and can lead to delayed aging, increased healthspan, and a remarkable extension of longevity.
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Growth hormone (GH) actions impact growth, metabolism, and body composition and have been associated with aging and longevity. Lack of GH results in slower growth, delayed maturation, and reduced body size and can lead to delayed aging, increased healthspan, and a remarkable extension of longevity.
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Growth and growth hormone: An overview
Growth Hormone & IGF Research, 2016Growth is a good indicator of a child's health. Growth disturbances, including short stature or growth failure, could be indications of illnesses such as chronic disease, nutritional deficits, celiac disease or hormonal abnormalities. Therefore, a careful assessment of the various requirements for normal growth needs to be done by history, physical ...
Robert Rapaport +2 more
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Growth hormone replacement for adult growth hormone deficiency
Expert Opinion on Pharmacotherapy, 2003Growth hormone deficiency (GHD) in childhood causes growth retardation, short stature and significant impairment of adult height. Growth hormone (GH) has been given successfully to these children for > 40 years but only since the introduction of recombinant DNA technology, has enough GH been available for paediatric needs and also for other indications.
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Extrapituitary growth hormone and growth?
General and Comparative Endocrinology, 2014While growth hormone (GH) is obligatory for postnatal growth, it is not required for a number of growth-without-GH syndromes, such as early embryonic or fetal growth. Instead, these syndromes are thought to be dependent upon local growth factors, rather than pituitary GH.
Harvey, Steve, Baudet, Marie-Laure
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