Short stature is a common reason for a child to visit the endocrinologist, and can be a variant of normal or secondary to an underlying pathologic cause. Pathologic causes include growth hormone deficiency (GHD), which can be congenital or acquired later.
Colleen O'Neill+2 more
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Adult growth hormone deficiency
Adult growth hormone deficiency (AGHD) is being recognized increasingly and has been thought to be associated with premature mortality. Pituitary tumors are the commonest cause for AGHD.
Vishal Gupta
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Growth hormone deficiency during young adulthood and the benefits of growth hormone replacement [PDF]
Until quite recently, the management of children with growth hormone deficiency (GHD) had focussed on the use of recombinant human GH (rhGH) therapy to normalise final adult height.
M Ahmid+3 more
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Nutritional Counseling in Children with Growth Hormone Deficiency Treated with Recombinant Human Growth Hormone: Analysis of Growth Response Parameters [PDF]
Background and Objectives: Growth failure is the main symptom of growth hormone deficiency (GHD) in children. The standard treatment for GHD is the administration of recombinant human growth hormone (rhGH).
Joanna Budzulak+2 more
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Prevalence of growth hormone deficiency in brain tumor survivors: a systematic review and meta-analysis [PDF]
Objective: To evaluate the prevalence of growth hormone deficiency in patients who underwent cranial irradiation for brain tumors. Methods: Ovid Medline and Embase databases were used for review.
Tatiana Tselovalnikova+5 more
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Diagnosing Growth Hormone Deficiency in Adults [PDF]
Adult growth hormone (GH) deficiency is a recognised syndrome associated with adverse phenotypic, metabolic, and quality-of-life features which improve in many patients when GH is substituted.
Nigel Glynn, Amar Agha
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Response to growth hormone according to provocation test results in idiopathic short stature and idiopathic growth hormone deficiency [PDF]
Purpose To investigate growth response in children with either idiopathic short stature (ISS) or growth hormone (GH) deficiency (GHD). Methods The data of prepubertal GHD or ISS children treated using recombinant human GH were obtained from the LG Growth
Ju Young Yoon+9 more
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Growth hormone in growth hormone deficiency [PDF]
Papers p 70 With the advent of an unlimited supply of recombinant DNA growth hormonesome 15 years ago endocrinologists and paediatricians hoped that the majorgoal in treating children with growth hormone deficiency—that is, a near normal adult height—would finally be achievable.
Jean-Claude Carel+2 more
openaire +5 more sources
Growth Hormone Deficiency [PDF]
Growth hormone deficiency is relative, not absolute. Conventional stimulation tests of hGH release do not recognise some children who will benefit from hGH treatment and it is probably justified, at this point, undertaking a six month trial of hGH in all short children who are growing slowly (less than 4 cm/yr).
openaire +6 more sources
Prolyl Endopeptidase-like Deficiency Associated with Growth Hormone Deficiency
Prolyl endopeptidase-like (PREPL) deficiency (MIM#616224) is a rare congenital disorder characterised by neonatal hypotonia and feeding difficulties, growth hormone (GH) deficiency and hypergonadotropic hypogonadism.
Laura Sayol-Torres+5 more
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