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Endocrines, 2022 Short stature is a common reason for a child to visit the endocrinologist, and can be a variant of normal or secondary to an underlying pathologic cause. Pathologic causes include growth hormone deficiency (GHD), which can be congenital or acquired later.
Colleen O'Neill +2 more
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Adult growth hormone deficiency
Indian Journal of Endocrinology and Metabolism, 2011 Adult growth hormone deficiency (AGHD) is being recognized increasingly and has been thought to be associated with premature mortality. Pituitary tumors are the commonest cause for AGHD.
Vishal Gupta
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Growth hormone deficiency during young adulthood and the benefits of growth hormone replacement [PDF]
Endocrine Connections, 2016 Until quite recently, the management of children with growth hormone deficiency (GHD) had focussed on the use of recombinant human GH (rhGH) therapy to normalise final adult height.
M Ahmid +3 more
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Nutritional Counseling in Children with Growth Hormone Deficiency Treated with Recombinant Human Growth Hormone: Analysis of Growth Response Parameters [PDF]
BiomedicinesBackground and Objectives: Growth failure is the main symptom of growth hormone deficiency (GHD) in children. The standard treatment for GHD is the administration of recombinant human growth hormone (rhGH).
Joanna Budzulak +2 more
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Response to growth hormone according to provocation test results in idiopathic short stature and idiopathic growth hormone deficiency [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2022 Purpose To investigate growth response in children with either idiopathic short stature (ISS) or growth hormone (GH) deficiency (GHD). Methods The data of prepubertal GHD or ISS children treated using recombinant human GH were obtained from the LG Growth
Ju Young Yoon +9 more
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Growth hormone in growth hormone deficiency [PDF]
BMJ, 2002 Papers p 70 With the advent of an unlimited supply of recombinant DNA growth hormonesome 15 years ago endocrinologists and paediatricians hoped that the majorgoal in treating children with growth hormone deficiency—that is, a near normal adult height—would finally be achievable.
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Growth Hormone Deficiency [PDF]
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1987 Growth hormone deficiency is relative, not absolute. Conventional stimulation tests of hGH release do not recognise some children who will benefit from hGH treatment and it is probably justified, at this point, undertaking a six month trial of hGH in all short children who are growing slowly (less than 4 cm/yr).
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Adult growth hormone deficiency [PDF]
Clinical Medicine, 2003 Growth hormone deficiency (GHD) in adults arises as a consequence of decreased secretion of somatotropin (GH) from the anterior pituitary. The diagnosis of GHD is dependent on the demonstration of a subnormal rise in serum GH in response to one or more dynamic stimulation tests in the presence of co-existing pituitary disease or other pituitary hormone
A M, Brooke, J P, Monson
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Prolyl Endopeptidase-like Deficiency Associated with Growth Hormone Deficiency
JCRPE, 2023 Prolyl endopeptidase-like (PREPL) deficiency (MIM#616224) is a rare congenital disorder characterised by neonatal hypotonia and feeding difficulties, growth hormone (GH) deficiency and hypergonadotropic hypogonadism.
Laura Sayol-Torres +5 more
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Growth hormone treatment for growth hormone deficient adults [PDF]
Journal of Clinical Pharmacy and Therapeutics, 1996 Growth hormone (GH) deficiency in adults is now recognized as a clinical syndrome with characteristic signs and symptoms. Numerous trials with daily subcutaneous biosynthetic human growth hormone (hGH) have been conducted in this patient group. Generally, improvements in insulin-like growth factor levels, decreases in total fat mass and increases in ...
W, Clark, M J, Kendall
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