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Short stature is a common reason for a child to visit the endocrinologist, and can be a variant of normal or secondary to an underlying pathologic cause. Pathologic causes include growth hormone deficiency (GHD), which can be congenital or acquired later.
Colleen O'Neill+2 more
doaj +2 more sources
Effect of growth hormone therapy on Taiwanese children with growth hormone deficiency [PDF]
Human growth hormone (GH) has been successfully used in children with GH deficiency (GHD). However, there are few published data on the effect of GH in Taiwanese children with GHD.
Ying-Hua Huang+3 more
doaj +3 more sources
Adult growth hormone deficiency
Adult growth hormone deficiency (AGHD) is being recognized increasingly and has been thought to be associated with premature mortality. Pituitary tumors are the commonest cause for AGHD.
Vishal Gupta
doaj +4 more sources
Growth hormone deficiency during young adulthood and the benefits of growth hormone replacement [PDF]
Until quite recently, the management of children with growth hormone deficiency (GHD) had focussed on the use of recombinant human GH (rhGH) therapy to normalise final adult height.
M Ahmid+3 more
doaj +4 more sources
Diagnosing Growth Hormone Deficiency in Adults [PDF]
Adult growth hormone (GH) deficiency is a recognised syndrome associated with adverse phenotypic, metabolic, and quality-of-life features which improve in many patients when GH is substituted.
Nigel Glynn, Amar Agha
doaj +3 more sources
Genetics of Isolated Growth Hormone Deficiency [PDF]
When a child is not following the normal, predicted growth curve, an evaluation for underlying illnesses and central nervous system abnormalities is required, and appropriate consideration should be given to genetic defects causing growth hormone (GH ...
E. Mullis, Primus
core +5 more sources
Effect of Growth Hormone (hGH) Replacement Therapy on Physical Work Capacity and Cardiac and Pulmonary Function in Patients with hGH Deficiency Acquired in Adulthood. [PDF]
The effects of 6 months of replacement therapy with recombinant human GH (hGH) on physical work capacity and cardiac structure and function were investigated in 20 patients with hGH deficiency of adult onset in a double blind, placebo-controlled trial ...
Huber, Rudolf M.+5 more
core +2 more sources
Response to growth hormone according to provocation test results in idiopathic short stature and idiopathic growth hormone deficiency [PDF]
Purpose To investigate growth response in children with either idiopathic short stature (ISS) or growth hormone (GH) deficiency (GHD). Methods The data of prepubertal GHD or ISS children treated using recombinant human GH were obtained from the LG Growth
Ju Young Yoon+9 more
doaj +1 more source
Growth hormone in growth hormone deficiency [PDF]
Papers p 70 With the advent of an unlimited supply of recombinant DNA growth hormonesome 15 years ago endocrinologists and paediatricians hoped that the majorgoal in treating children with growth hormone deficiency—that is, a near normal adult height—would finally be achievable.
Jean-Claude Carel+2 more
openaire +5 more sources
Growth Hormone Deficiency [PDF]
Growth hormone deficiency is relative, not absolute. Conventional stimulation tests of hGH release do not recognise some children who will benefit from hGH treatment and it is probably justified, at this point, undertaking a six month trial of hGH in all short children who are growing slowly (less than 4 cm/yr).
openaire +6 more sources