Results 141 to 150 of about 304,424 (378)

Developments in the Management of Growth Hormone Deficiency: Clinical Utility of Somapacitan

Drug Design, Development and Therapy
Bradley S Miller,1 Jo Blair,2 Reiko Horikawa,3 Agnès Linglart,4– 7 Kevin CJ Yuen8 1Division of Pediatric Endocrinology, University of Minnesota Medical School, MHealth Fairview Masonic Children’s Hospital, Minneapolis, MN, USA; 2Department of Paediatric ...
Miller BS, Blair J, Horikawa R, Linglart A, Yuen KC   +4 more
doaj  

Modeling Iodine Deficiency [PDF]

arXiv
This paper presents a four-unit, four-component mathematical model of iodine metabolism and its impact on thyroid hormone levels in the body. We focus on the relationships between iodine (I-), triiodothyronine (T3), thyroxine (T4), and thyroid-stimulating hormone (TSH) through the mixer, thyroid, sensor (pituitary gland), and metabolism. Iodine plays a
arxiv  

Transient elastography and controlled attenuation parameter (CAP) in the assessment of liver steatosis in severe adult growth hormone deficiency [PDF]

, 2019
Non-alcoholic fatty liver disease (NAFLD) is common in patients with growth hormone deficiency (GHD). Some noninvasive techniques have been used to quantify liver fat, such as the controlled attenuation parameter (CAP).
Ferro, André Metzker, Furtado, Adriana Claudia Lopes Carvalho, Louro, Daniela Mariano Carvalho, Montenegro, Maria Luiza Ricardo Nogueira, Naves, Luciana Ansaneli, Pirangi, Patrícia Souza, Regattieri, Neysa Aparecida Tinoco, Rodrigues, Marcelo Palmeira   +7 more
core   +1 more source

Plasma Growth Hormone, Insulin, and Glucagon Responses to Arginine Infusion in Children and Adolescents with Idiopathic Short Stature, Isolated Growth Hormone Deficiency, Panhypopituitarism, and Anorexia Nervosa [PDF]

, 1975
Pierre C. Sizonenko, Alexander Rabinovitch, Pierre Schneider, L Paunier, Claes B. Wollheim, G Zahnd   +5 more
openalex   +1 more source

On the Relentless Pursuit of an Oral Insulin Delivery System: How Far is Too Far?

Advanced Therapeutics, EarlyView.
Injectable insulin preparations have far outpaced oral ones by virtue of adequate bioavailability and are driven by innovations, including insulin pumps, real‐time blood glucose monitoring, and artificial intelligence. In contrast, oral insulin delivery systems, including nanomedicines, continue to struggle and lag due to varied reasons.
Sourav Bhattacharjee
wiley   +1 more source

The Effectiveness of Oxandrolone in Promoting Linear Growth in Growth Hormone Deficient Children [PDF]

, 1973
This two-year study consisted of a comparison of oxandrolone and growth hormone for the treatment of five children with documented growth hormone deficiency.
Mellinger, Raymond C., Morrow, Lewis B., Saeed-uz Zafar, M., Wolf, Charles B.   +3 more
core   +1 more source

Isolated growth hormone deficiency: Two families with autosomal dominant inheritance [PDF]

, 1974
E.M.E. Poskitt, P H Rayner
openalex   +1 more source

Guidelines for the treatment of growth hormone excess and growth hormone deficiency in adults

Journal of Endocrinological Investigation, 2008
The V Consensus Group Meeting on 'Guidelines for Treatment of GH Excess and GH Deficiency in the Adult' was an international workshop held on February 20-22, 2006 in Santa Monica, California, USA. The principal aim of this meeting was to provide guidelines for the evaluation and treatment of adults with either form of abnormal GH secretion: GH excess ...
GIUSTINA, Andrea, Barkan A, Chanson P, Grossman A, Hoffman A, Ghigo E, Casanueva F, Colao A, Lamberts S, Sheppard M, Melmed S, Pituitary Society, European Neuroendocrine Association   +12 more
openaire   +9 more sources

Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation

Advanced Science, EarlyView.
The study deciphers the landscapes of lineage‐related transcription factors in prostatic adenocarcinoma and neuroendocrine prostate cancer using an innovative approach. These findings, validated across cohorts, highlight TFs' roles in cell development and offer novel therapeutic targets.
Yu Wang, Hui Xue, Xiaohui Zhu, Dong Lin, Zheng Chen, Xin Dong, Junru Chen, Mingchen Shi, Yuchao Ni, Jonathan Cao, Rebecca Wu, Connie Kang, Xinyao Pang, Francesco Crea, Yen‐Yi Lin, Colin C. Collins, Martin E. Gleave, Abhijit Parolia, Arul Chinnaiyan, Christopher J. Ong, Yuzhuo Wang   +20 more
wiley   +1 more source

The results of long-term growth hormone replacement therapy in Turkish children with growth hormone deficiency

The Turkish Journal of Pediatrics, 1998
From a total of 118 patients treated for growth hormone deficiency, 37 (23 boys, 14 girls) have reached their final height. Twenty-five patients had isolated growth hormone deficiency (IGHD) and 12 had multiple pituitary hormone deficiency (MPHD).
N Yordam, N Kandemir, A Alikaşifoğlu
doaj