Results 151 to 160 of about 280,040 (307)

Thyroid function in children with growth hormone deficiency during long-term growth hormone replacement therapy

Central European Journal of Immunology, 2018
Ewelina Witkowska-Sędek, Ada Borowiec, Anna Majcher, Maria Sobol, Małgorzata Rumińska, Beata Pyrżak   +5 more
doaj   +1 more source

Morphological changes and lateralization of the thalamic nuclei in children with growth hormone deficiency. [PDF]

Front Endocrinol (Lausanne)
Lee JY, Lim SM, Oh JH, Kim H, Lee GY, Lee BG, Hoh JK, Yang S, Lee HJ.   +8 more
europepmc   +1 more source

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Adult Growth Hormone Deficiency and Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]

Curr Obes Rep
Polyzos SA, Mantovani A, Targher G.
europepmc   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Potential impacts of adult growth hormone deficiency: a population-based study in England. [PDF]

BMJ Open
Criseno S, Gayton E, Araghi M, Machtiger-Azoulay N, Toogood A.   +4 more
europepmc   +1 more source

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

Serum osteocalcin as a novel biomarker for differentiating growth hormone deficiency from idiopathic short stature. [PDF]

Front Endocrinol (Lausanne)
Wang Y, Zhou H, Wang H, Ma J, Chen X, Yang H, Zheng H, Wang A.   +7 more
europepmc   +1 more source

A pituitary adenoma secreting high molecular weight adrenocorticotropin without evidence of Cushing's disease [PDF]

, 1987
Allolio, B., Kaulen, D., Reincke, Martin, Saeger, W., Winkelmann, W.   +4 more
core   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source