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Diagnosis of Growth Hormone Deficiency
2010The diagnosis of growth hormone deficiency (GHD) was essentially a clinical one prior to the advent of radioimmunoassay in the mid-1960s. From this point on both clinical and biochemical serum GH responses to a variety of provocation tests were used to define the condition. The definition of an adequate GH response to stimulation has changed over time,
E A, Webb, M T, Dattani
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Adult Growth Hormone Deficiency
Hormone Research, 2008Several reports have focused on the clinical features of the untreated GH-deficient adult and the effect of GH therapy. The results reported are strikingly unanimous. Untreated GH-deficient adults have been shown to have increased cardiovascular mortality, reduced exercise capacity, reduced muscle strength, subnormal glomerular filtration rate and ...
J O, Jørgensen +7 more
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Growth hormone therapy for adult growth hormone deficiency
Trends in Endocrinology & Metabolism, 1996GH deficiency in adult life is associated with a number of adverse biological changes including osteopenia, reduced exercise capacity, altered body composition, deleterious alterations in the lipid profile and insulin status, and reduced quality of life. Potentially, most of these changes can be reversed by GH replacement therapy.
S M, Shalet, A, Rahim, A A, Toogood
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Growth hormone deficiency in children
Best Practice & Research Clinical Endocrinology & Metabolism, 2016PRODAM, Flavia +2 more
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TESTS FOR GROWTH HORMONE DEFICIENCY
The Lancet, 1986IanR. Gunn, P.C. Hindmarsh, C.G.D. Brook
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Human growth hormone deficiency
The Indian Journal of Pediatrics, 1983P S, Menon, A K, Deorari, R K, Menon
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Diagnosis of growth hormone deficiency
Journal of Endocrinological Investigation, 1994openaire +2 more sources