Archives of Endocrinology and Metabolism, 2022 SUMMARY We present the unique case of an adult Brazilian woman with severe short stature due to growth hormone deficiency with a heterozygous G to T substitution in the donor splice site of intron 3 of the growth hormone 1 (GH1) gene (c.291+1G>T).
Julia Haddad Labello +8 more
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Consensus guidelines for the diagnosis and treatment of adults with growth hormone deficiency: Summary statement of the growth hormone research society workshop on adult growth hormone deficiency [PDF]
, 1998 Based on the increasing body of evidence that adults with GH deficiency (somatotropin deficiency) have impaired health that improves with GH replacement, many countries have already approved the use of GH for replacement therapy in adults with GH ...
Clemmons, David +1 more
core +2 more sources
Effect of growth hormone therapy on Taiwanese children with growth hormone deficiency
Journal of the Formosan Medical Association, 2012 Human growth hormone (GH) has been successfully used in children with GH deficiency (GHD). However, there are few published data on the effect of GH in Taiwanese children with GHD.
Ying-Hua Huang +3 more
doaj +1 more source
Consensus guidelines for the diagnosis and treatment of growth hormone (GH) deficiency in childhood and adolescence: Summary statement of the GH research society [PDF]
, 2000 The diagnosis and treatment of GH deficiency (GHD) during childhood and adolescence have been the subject of much controversy (1–3). To insure that patients are appropriately identified and treated, the GH Research Society (GRS) convened a workshop, on ...
Clemmons, David +1 more
core +2 more sources
Evaluation of cases with growth hormone deficiency
Acta Medica Alanya, 2019 Aim:The purpose of this study was to elicit data concerning the clinical and laboratory features of children with growth hormone deficiency monitored by the Pediatric Endocrinology and Metabolism Polyclinic in order to produce useful information for ...
Meltem Di̇rek +3 more
doaj +1 more source
Laron syndrome: An experience of treatment of two cases
Journal of Clinical and Translational Endocrinology Case Reports, 2021 Laron syndrome or growth hormone insensitivity is a rare disease presenting with severe postnatal growth failure. Clinically, in most circumstances, it is indistinguishable from growth hormone deficiency.
Hiya Boro +4 more
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Recovery from neurological sequelae secondary to oncological brain surgery in an adult growth hormone-deficient patient after growth hormone treatment [PDF]
, 2009 [Abstract] Objective: To report an unusual case of significant neurological recovery in a 26-year-old growth hormone-deficient female patient with significant neurological sequelae resulting from brain surgery at 11 years of age.
Arce, Víctor Manuel +6 more
core +3 more sources
Adult growth hormone deficiency [PDF]
Clinical Medicine, 2003 Growth hormone deficiency (GHD) in adults arises as a consequence of decreased secretion of somatotropin (GH) from the anterior pituitary. The diagnosis of GHD is dependent on the demonstration of a subnormal rise in serum GH in response to one or more dynamic stimulation tests in the presence of co-existing pituitary disease or other pituitary hormone
A M Brooke, John P. Monson
openaire +3 more sources
Defective minor spliceosome mRNA processing results in isolated familial growth hormone deficiency [PDF]
, 2014 The molecular basis of a significant number of cases of isolated growth hormone deficiency remains unknown. We describe three sisters affected with severe isolated growth hormone deficiency and pituitary hypoplasia caused by biallelic mutations in the ...
Ali Oghabian +11 more
core +2 more sources
Oman Medical Journal, 2017 Objectives: The use of growth hormone (GH) in idiopathic short stature (ISS) has been a subject of debate for the past two decades. We sought to assess the effect of GH on final height (FH) in patients with ISS in our region, which has a high ...
Shireen Mreish +2 more
doaj +1 more source