Results 51 to 60 of about 513,834 (341)

Growth hormone deficiency in cleft lip and palate patients [PDF]

open access: yesJournal of Analytical Research in Clinical Medicine, 2015
Introduction: Failure to thrive (FTT) is relatively common among cleft patients, most commonly attributed to feeding problems during the first months of life.
Shahin AbdollahiFakhim   +4 more
doaj   +1 more source

Growth Hormone Treatment for Growth Hormone Deficiency and Idiopathic Short Stature: New Guidelines Shaped by the Presence and Absence of Evidence

open access: yesCurrent opinion in pediatrics, 2017
Purpose of review The Pediatric Endocrine Society recently published new guidelines for the use of human growth hormone (hGH) and human insulin-like growth factor-I (hIGF-I) treatment for growth hormone deficiency, idiopathic short stature, and primary ...
A. Grimberg, D. Allen
semanticscholar   +1 more source

Response to Growth Hormone Treatment in Isolated Growth Hormone Deficiency versus Multiple Pituitary Hormone Deficiency

open access: yes, 2021
Background: Growth hormone (GH) therapy successfully increases height prognosis in children with GH deficiency (GHD); however, adult height data are still limited. Aim: This study investigated near-adult height (NAH) in patients with idiopathic GHD (i.e.
Darendeliler, Fatma Feyza   +2 more
core   +1 more source

Diez años de experiencia con el primer biosimilar autorizado de hormona del crecimiento recombinante humana en la práctica clínica habitual

open access: yesAnales de Pediatría, 2018
Resumen: Introducción: La hormona de crecimiento humana recombinante biosimilar (rhGH) fue el primer medicamento autorizado por la Agencia Europea del Medicamento (EMA), en el año 2006, por la vía de registro biosimilar.
Juan Pedro López-Siguero   +4 more
doaj   +1 more source

Understanding burden of illness for child growth hormone deficiency

open access: yesQuality of Life Research, 2017
PurposeResearch demonstrates that children and adolescents with growth hormone deficiency (GHD) are impacted in multiple ways beyond their short stature; however, there are no disease-specific measures to assess these impacts.
M. Brod   +5 more
semanticscholar   +1 more source

Clinical Indications for Growth Hormone Therapy

open access: yesAdvances in Pediatrics, 2022
Growth hormone (GH) is an injectable medication originally used to replace the deficiency of the hormone, but has expanded to treating conditions that may reduce growth and adult height even when the body maintains endogenous GH production. In the United
Melinda Danowitz, A. Grimberg
semanticscholar   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

The use of recombinant human growth hormone in patients with Mucopolysaccharidoses and growth hormone deficiency: a case series

open access: yesItalian Journal of Pediatrics, 2019
Background The treatment with recombinant human growth hormone in patients affected by Mucopolysaccharidoses (MPS) is considered whenever a concurrent diagnosis of growth hormone deficiency is demonstrated. The short- and long-term effects of recombinant
A. Cattoni   +5 more
doaj   +1 more source

Efficacy of growth hormone therapy in adults with childhood-onset growth hormone deficiency [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2014
PurposeGrowth hormone (GH) plays a key role in the regulation of body composition, lipid metabolism, and quality of life in adults with GH deficiency (GHD).
Ja Hye Kim   +3 more
doaj   +1 more source

Pharmacokinetic and Pharmacodynamic Modeling of MOD-4023, a Long-Acting Human Growth Hormone, in Growth Hormone Deficiency Children

open access: yesHormone Research in Paediatrics, 2017
Background/Aims: MOD-4023 is a long-acting human growth hormone (hGH) in clinical trials for the treatment of growth hormone deficiency (GHD). A key goal is maintenance of serum concentrations of insulin-like growth factor (IGF) 1 within normal range ...
D. Fisher   +5 more
semanticscholar   +1 more source

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