Results 21 to 30 of about 892,121 (262)
Numerous molecular mechanisms are being examined in an attempt to discover disease-modifying drugs to slow down the underlying neurodegeneration in Alzheimer’s disease.
Heba M Mansour +3 more
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O objetivo deste trabalho foi avaliar o desenvolvimento e a produtividade de colmos de cana-de-açúcar, resultantes da aplicação de reguladores vegetais no iníco da safra.
Glauber Henrique Pereira Leite +1 more
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In poplar clones with different resistance to the fungus Ceratocystis fimbriata growth of shoots, intensity of transpiration and the level of endogenous growth regulators were determined. More resistant clones, Populus 'Robusta' and P.
Jadwiga Stopińska
doaj +1 more source
Pathophysiological mechanisms of cardiotoxicity in chemotherapeutic agents
Certain success has been achieved in the treatment of cancer due to the development of various effective chemotherapeutic drugs. However, an increase in their effectiveness (aggressiveness) was associated with a growth of undesirable effects on the ...
Aleksey M. Chaulin +2 more
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Interspecific differences between D. pulex and D. magna in tolerance to cyanobacteria with protease inhibitors. [PDF]
It is known that cyanobacteria negatively affect herbivores due to their production of toxins such as protease inhibitors. In the present study we investigated potential interspecific differences between two major herbivores, Daphnia magna and Daphnia ...
Christian J Kuster, Eric Von Elert
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Nephrotoxicity induced by vascular endothelial growth factor inhibitors [PDF]
Vascular endothelial growth factor (VEGF) is a special mitogen for vascular endothelial cells, an essential endogenous angiogenic cytokine, and the principal controller of vascular growth that plays a fundamental role in therapeutic angiogenesis pathways.
Shirinsadat Badri +5 more
doaj +1 more source
Targeting the mTOR Complex by Everolimus in NRAS Mutant Neuroblastoma.
High-risk neuroblastoma remains lethal in about 50% of patients despite multimodal treatment. Recent attempts to identify molecular targets for specific therapies have shown that Neuroblastoma RAS (NRAS) is significantly mutated in a small number of ...
Michael K Kiessling +8 more
doaj +1 more source
Fibroblast Growth Factor Inhibitors [PDF]
Dr. Ignatio Witsuba (MD Anderson) started this session by giving an overview of the fibroblast growth factor (FGF) pathway and expression of FGFs (22 members), FGF receptors (FGFRs, four members), and their gene family members in non-small cell lung cancer (NSCLC).
openaire +2 more sources
Background: The efficacy of next-generation epidermal growth factor receptor-tyrosine kinase inhibitors in patients with advanced non-small cell lung cancer who have failed first-generation epidermal growth factor receptor-tyrosine kinase inhibitors ...
Yi-Tian Qi MM +2 more
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Background While cancer is a risk factor for developing thromboembolism, so is the use of molecularly targeted therapies. This study aimed to determine whether thromboembolism incidence differed between vascular endothelial growth factor (VEGF) and ...
Ryo Takada +4 more
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