Results 31 to 40 of about 6,449,139 (275)

Decreased Growth with Serotonin Reuptake Inhibitors

open access: yesPediatric Neurology Briefs, 2002
Growth and growth hormone secretion were evaluated in 4 children (3 boys), aged 11.6 to 13.7 years, treated with selective serotonin reuptake inhibitors (SSRIs) for obsessive compulsive disorder or Tourette syndrome, at Schneider Children’s Medical ...
J Gordon Millichap
doaj   +1 more source

Factors associated with efficacy of first-generation epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer

open access: yesTumor Biology, 2017
The finding of epidermal growth factor receptor tyrosine kinase inhibitors, which reflects a classical process of translational research, is a critical milestone for non-small-cell lung cancer treatment.
Shaohua Cui, Liyan Jiang
doaj   +1 more source

DeepPurpose-based drug discovery in chondrosarcoma

open access: yesChinese Journal of Plastic and Reconstructive Surgery, 2022
Background: Chondrosarcoma (CS) is the second most common primary bone tumor, accounting for approximately 30% of all malignant bone tumors. Unfortunately, the efficacy of currently available drug therapies is limited.
Jianrui Li   +3 more
doaj   +1 more source

IMPACT OF PLANT GROWTH INHIBITORS ON THE GROWTH AND YIELD OF SORGHUM

open access: yesThe Iraqi Journal of Agricultural science, 2021
Field experiment was carried out during the spring and fall seasons of 2019 at the Abu Ghraib Research Station of the Agricultural Research Office/ Ministry of Agriculture, was aimed to investigate the effect of plant growth inhibitors on growth and ...
N. M. Abood, E. M. SHALAL, M. I. HAMDAN
doaj   +1 more source

Fibroblast Growth Factor Inhibitors [PDF]

open access: yesJournal of Thoracic Oncology, 2010
Dr. Ignatio Witsuba (MD Anderson) started this session by giving an overview of the fibroblast growth factor (FGF) pathway and expression of FGFs (22 members), FGF receptors (FGFRs, four members), and their gene family members in non-small cell lung cancer (NSCLC).
openaire   +2 more sources

Identifying tumor cell growth inhibitors by combinatorial chemistry and zebrafish assays. [PDF]

open access: yesPLoS ONE, 2009
Cyclin-dependent kinases (CDKs) play important roles in regulating cell cycle progression, and altered cell cycles resulting from over-expression or abnormal activation of CDKs observed in many human cancers.
Jing Xiang   +9 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan   +18 more
wiley   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade.

open access: yesPLoS ONE, 2017
Previous data indicate that Tankyrase inhibitors exert anti-growth functions in many cancer cell lines due to their ability to inactivate the YAP protooncogene.
Jiaoyuan Jia   +7 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz   +12 more
wiley   +1 more source

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