Results 141 to 150 of about 1,188,466 (313)

Strigolactone: An Emerging Growth Regulator for Developing Resilience in Plants. [PDF]

Plants (Basel), 2022
Alvi AF, Sehar Z, Fatma M, Masood A, Khan NA.   +4 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Cotton response to growth regulator Pix

California Agriculture, 1983
It controlled rank plant growth but had no significant effect on ...
T Kerby
doaj  

Plant growth regulator extracts from seaweeds promote plant growth and confer drought tolerance in canola (<i>Brassica napus</i>). [PDF]

Plant Signal Behav, 2023
Nichol JB, Ribano AKB, Hickerson NMN, Ali N, Jamois F, Samuel MA.   +5 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Growth regulator controls tomato transplant height

California Agriculture, 1989
A new plant growth regulator, uniconazole, controlled height of greenhouse-grown fresh market tomato transplants in a 1-year trial. Field results showed no effect on final yields and quality.
G Hickman, E Perry, R Mullen, R Smith
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Meta-QTL analysis for mining key genes associated with seed oil content in maize

BMC Plant Biology
Background Maize seed oil plays a significant role in human nutrition, animal feed, and bioenergy applications. Despite extensive quantitative trait loci (QTL) studies conducted on this trait, the broad confidence intervals of the identified QTLs have ...
Zilong Zhao, Ke Li, Wei Wang, Fei Yi, Nan Zheng, Jinsheng Lai, Qiujie Liu, Jian Chen   +7 more
doaj   +1 more source

Ovary Dissection Is a Sensitive Measure of Sterility in <i>Anopheles gambiae</i> Exposed to the Insect Growth Regulator Pyriproxyfen. [PDF]

Insects, 2023
Soto A, Rowland M, Messenger LA, Kirby M, Mosha FW, Manjurano A, Protopopoff N.   +6 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source