Results 91 to 100 of about 402,737 (273)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Plant-Growth Substances and Penicillium notatum [PDF]

open access: bronze, 1945
S. W. Lee, Edan Foley, Jeanne A. Epstein
openalex   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

Isolation of Allelopathic Substances in Rice Seedlings

open access: yesPlant Production Science, 2002
In order to evaluate the allelopathic potential of the early developmental stage of rice plants (Oryza sativa L.), a search for allelopathic substances was undertaken in acetone extract of 10-d-old rice seedlings.
Hisashi Kato-Noguchi
doaj   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

open access: yesMolecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang   +10 more
wiley   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

Discrete-time model for a substance motion in a channel of a network. Application to a human migration channel [PDF]

open access: yesarXiv, 2018
We discuss a discrete-time model for motion of substance in a channel of a network. For the case of stationary motion of the substance and for the case of time-independent values of the parameters of the model we obtain a new class of statistical distributions that describe the distribution of the substance along the nodes of the channel.
arxiv  

Structure-Activity of Plant Growth Bioregulators and Their Effects on Mammals

open access: yesMolecules
In this review, we emphasize structure-activity and the effects on mammals of plant growth bioregulators. plant growth bioregulators can be referred to as “biochemical effectors” since they are substances having biological activity.
Zeno Garban, Gheorghe Ilia
doaj   +1 more source

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