Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
The growth of plant embryos in vitro. Preliminary experiments on the rôle of accessory substances [PDF]
, 1938 openalex +1 more source
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Acenaphtnylmercaptoalkanocarboxylic acids as plant growth substances
Acta Societatis Botanicorum Poloniae, 2015 E. Gawroński, W. Podkościelny
doaj +1 more source
The Substitution of Complexing Substances for Boron in Plant Growth
, 1957 J. R. Skok
openalex +2 more sources
Absorption of Growth-Promoting Substances by Cuttings [PDF]
, 1938 T. H. Jackson
openalex +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
THE EFFECT OF CERTAIN COLLOIDAL SUBSTANCES ON THE GROWTH OF WHEAT SEEDLINGS
, 1919 DAVID STOUT JENNINGS
openalex +2 more sources
Phospholipids and Related Substances as Growth Substrates for Soil Microorganisms1 [PDF]
, 1956 Albert Schatz +2 more
openalex +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source