Results 141 to 150 of about 402,737 (273)

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

On the chemical reactions occurring between certain substances which inhibit bacterial growth and the constituents of bacteriological media [PDF]

, 1942
A. E. Oxford
openalex   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Growth-promoting and Growth-inhibiting Substances in the Petiole

, 1940
Yasuyuki Okabe
openalex   +2 more sources

Nicotinic Acid as a Growth Accessory Substance for the Diphtheria Bacillus [PDF]

, 1937
J. Howard Mueller
openalex   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

A GROWTH INHIBITORY SUBSTANCE FOR THE INFLUENZA GROUP OF ORGANISMS IN THE BLOOD OF VARIOUS ANIMAL SPECIES [PDF]

, 1938
Elma Krumwiede, Ann G. Kuttner
openalex   +1 more source

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

First-trimester maternal concentrations of polyfluoroalkyl substances and fetal growth throughout pregnancy

Environment International, 2019
Background: Several studies have investigated the possible association between prenatal exposure to perfluoroalkyl substances (PFASs) and birth anthropometry. However, none has assessed fetal size longitudinally.
Olga Costa, Carmen Iñiguez, Cyntia B. Manzano-Salgado, Pilar Amiano, Mario Murcia, Maribel Casas, Amaia Irizar, Mikel Basterrechea, Andrea Beneito, Thomas Schettgen, Jordi Sunyer, Martine Vrijheid, Ferran Ballester, Maria-Jose Lopez-Espinosa   +13 more
doaj  

Do Broth Culture Filtrates Contain a Bacterial Growth-Inhibiting Substance? [PDF]

, 1931
L. A. Barnes
openalex   +1 more source