Results 201 to 210 of about 386,281 (303)

Impact of changes in cellular bioactive substances of amniotic fluid on the development of fetal growth restriction and preterm labor

, 2017
N. A. Drukker, N. V. Ermolova, V. V. Avrutskaya, Z. V. Zenkina, E. O. Shkotova, O.A. Durnitsyna, L. L. Erdzhanyan   +6 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Pharmacological Effects of Humic Substances and Their Signaling Mechanisms. [PDF]

Molecules
Zykova MV, Trofimova ES, Azarkina LA, Lasukova TV, Mihalyov DA, Drygunova LA, Danilets MG, Ligacheva AA, Tsupko AV, Bashirov SR, Belousov MV.   +10 more
europepmc   +1 more source

Effects of Water Deficit and Different some Substances Foliar Sprays on Growth, Antioxidants and Biochemical Components in Loquat (Eriobotrya japonica) Seedlings

Doaa M. Hamza, M. A. El-Sherpiny, Doaa S. Mahmoud   +2 more
openalex   +1 more source

Studies on application of growth substances to increase yield in sweet potatoes. II

, 1951
Hiroyuki Mori, S. Tsuchiya
openalex   +2 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Marine Microbial Exopolysaccharides (EPSs): Untapped Bio-Reserves. [PDF]

Polymers (Basel)
Aslam B, Khalid MH, Aljasir SF.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Metabolomic Analysis of Antifungal Secondary Metabolites from <i>Achaetomium sophora</i> HY17 in Co-Culture with <i>Botrytis cinerea</i> HM1. [PDF]

Microorganisms
Liu G, Tang Z, Wang R, Xin Y, Gu P.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source