Criteria for the Diploma qualifications in science at foundation and higher levels [PDF]
core
Imperial strategy of cancer cells through mitochondrial transfer
Cangkrama et al. demonstrated that cancer cells donate their mitochondria to fibroblasts through mitochondrial transfer, reprogramming them into ‘MitoCAF’. Likewise, our group has identified mitochondrial transfer from cancer cells to tumor infiltrating lymphocytes, resulting in mitochondrial ‘hijack’ and impaired antitumor immunity.
Takamasa Ishino, Yosuke Togashi
wiley +1 more source
Quality Control Strategies for Pit Mud Based on the Synergistic Effects of Flavor, Microorganisms and Physicochemical Factors. [PDF]
Sun L +5 more
europepmc +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
The Effects of Three Phenolic Substances on the Growth and Digestive Physiology of the Fall Armyworm <i>Spodoptera frugiperda</i> (Lepidoptera: Noctuidae). [PDF]
Lv JY, Deng YN, Liu XR, Niu D, Zhang WS.
europepmc +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Diverse biofilm-forming <i>Sphingomonadaceae</i> represent twelve novel species isolated from glaciers on the Tibetan Plateau. [PDF]
Han D, Xin YH, Liu Q.
europepmc +1 more source
RAS‐targeted therapies have become a clinical reality. Although promising results in patients have been achieved, there are still challenges ahead such as coping with drug resistance. Here we summarize selected RAS inhibitors targeting either individual KRAS mutant isoforms (KRASG12C, KRASG12D, KRASG12V) or exhibiting a wider inhibitory spectrum ...
Matthias Drosten, Mariano Barbacid
wiley +1 more source
Nanostructured Dual-Delivery System with Antioxidant and Synergistic Approach for Targeted Dermal Treatment. [PDF]
Dzurická L +5 more
europepmc +1 more source

