Results 231 to 240 of about 8,075,360 (336)
A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker +3 more
wiley +1 more source
Biochar in Animal Agriculture: Enhancing Health, Efficiency and Environmental Sustainability. [PDF]
Kazemi M.
europepmc +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Recent progress on the biological degradation and solubilization of coal. [PDF]
Sekhohola-Dlamini LM +4 more
europepmc +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
Developing a prognostic model for predicting preterm birth using a machine learning algorithm. [PDF]
Abdi F +5 more
europepmc +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
New enlightenment on the regulatory effects of acids and phenolic compounds in wood vinegar, a by-product of biomass pyrolysis, on tomato production. [PDF]
Zhou H +5 more
europepmc +1 more source

