Results 241 to 250 of about 1,208,663 (362)

Variation in growth traits and biological activities among wild watercress (Nasturtium officinale L.) populations in Iran. [PDF]

Sci Rep
Karkon Zonuzi N, Mirjalili MH, Esmaeili H, Sonboli A.   +3 more
europepmc   +1 more source

In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium‐Dependent β‐Catenin Activation

Advanced Science, EarlyView.
We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun, Xu Yang, Wenchao Jiang, Chengbo Ji, Yingying Wu, Haoyu Sun, Xinyou Liu, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Junjie Zhao, Yuanyuan Ruan, Haojie Li, Xuefei Wang   +13 more
wiley   +1 more source

Genotype by environment interaction for growth traits of families of <i>Acacia melanoxylon</i> based on BLUP and GGE biplot. [PDF]

Front Plant Sci
Ruan SN, Chen LB, Zhang B, Zhang WH, Ding GC, Cao GQ, Ye LT, He SB, Shen DY, Yan Q.   +9 more
europepmc   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Detection of Genetic Polymorphism in Growth Hormone Receptor Gene and Its Influence on Growth Traits in Kari and Balkhi Sheep. [PDF]

Vet Med Sci
Al-Khalaifah H, Kiran M, Khan SH, Ulhaq I, Ibrahim M, Ahmad S, Bilal H, Shenming Z, Naz S, Khan RU, Alhidary IA.   +10 more
europepmc   +1 more source

Behaviour, Growth Performance, Foot Pad Quality, Bone Density and Carcass Traits of Broiler Chickens Reared with Barrier Perches and fed Different Dietary Crude Protein Levels [PDF]

, 2016
C.J. Bench, Matt Oryschak, D.R. Korver, E. Beltranena   +3 more
openalex   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Deciphering autosomal and X-linked genetic effects of early growth traits in Murciano-Granadina goats via a multivariate animal model. [PDF]

Vet Anim Sci
Ehsaninia J, Zandi MB, Taned M, Bagheripour A.   +3 more
europepmc   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Mutual information stacking method for prediction of the growth traits in pigs. [PDF]

Brief Bioinform
Su R, Huang B, Tan J, Shen Z, Zhong P, Liu J.   +5 more
europepmc   +1 more source