Results 61 to 70 of about 329,443 (268)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Meta‐Analysis of Genetic Parameters for Growth and Carcass Traits in Japanese Quail

open access: yesVeterinary Medicine and Science
Background The considerable variability observed in genetic parameters for growth and carcass traits in Japanese quails necessitates a meta‐analysis for their accurate estimation.
Maryam Sokhan   +2 more
doaj   +1 more source

Crossing system application and its effect on lambs growth traits [PDF]

open access: yesBiotechnology in Animal Husbandry, 2015
Success of crossing depends on the breeds used and the genetic distance among them, as well the combining ability of maternal and individual heterosis to make the proper choice of breeds employed in a crossing system. The aim of this study is to find the
Caro-Petrović V.   +7 more
doaj  

Snps detected in the sirt1 and h-fabp genes and their association with growth traits in yak [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2019
The aims of this study were to investigate whether the Sirtuin 1 (SIRT1) and Hear fatty acid binding protein (H-FABP) genes could be used as candidate genes in the breeding of yak. In 409 indigenous Chinese yaks, two single nucleotide polymorphisms (SNPs)
Linsheng GUI   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Phenotypic Evaluation of a Hybrid Diploid Blueberry Population for Plant Development and Fruit Quality Traits

open access: yesAgronomy, 2020
A diploid blueberry mapping population, used previously to map quantitative trait loci (QTL) for chilling requirement and cold hardiness, was evaluated for several plant development and fruit quality traits. Specifically, the population was phenotyped in
Lisa J. Rowland   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Genetic researches on growth traits of Japanese quail

open access: yesAIP Conference Proceedings, 2017
The main objective of the poultry industry is to increase genetic capacity of animals. Growth is one of the most important economic trait in poultry production. Thus, to obtain genetically superior animals related to growth traits is one of the most important issues of poultry breeding programs.
openaire   +1 more source

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