Results 81 to 90 of about 329,443 (268)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Perinatal brain growth and autistic traits in toddlers

Translational Psychiatry
Abstract Background: Autism is a heterogeneous set of neurodevelopmental conditions with a significant heritable component and perinatal origins. The earliest observable behavioural traits with which a diagnosis can be made emerge at 18 months of age.
A. Tsompanidis, K. M. Chang, Y. T. Khan, M. A. Radecki, L. Dorschmidt, S. Hampton, E. Aydin, C. Allison, R. Tait, R. A. I. Bethlehem, V. Kyriakopoulou, T. Austin, J. Suckling, R. Holt, S. Baron-Cohen   +14 more
openaire   +5 more sources

Problematic Internet Use in Frontotemporal Dementia: A Case Series

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The present study investigated problematic internet use (PIU) among 61 patients with frontotemporal dementia (FTD) compared to a cohort of 354 patients with mild cognitive impairment (MCI) and Alzheimer's dementia. PIU was identified in 22.9% of FTD patients compared to only 0.8% of AD patients (p < 0.001). Behaviors included compulsive social
Daniele Urso, Giuseppe Volpe, Agnese Valguarnera, Davide Vilella, Alessandra Vitulli, Valentina Gnoni, Alessia Giugno, Eleonora Rollo, Mark D. Griffiths, Giancarlo Logroscino   +9 more
wiley   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Physician‐Scientist Pipeline for Pediatric Rheumatology: The Current Landscape and Future Perspectives

Arthritis Care &Research, EarlyView.
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu, Linda T. Hiraki, Mara L. Becker   +2 more
wiley   +1 more source

Estimates of Genetic and Phenotypic Trends of Growth Traits in Bali Cattle

Media Peternakan, 2012
The aim of this study was to estimate genetic and phenotypic trends for growth traits including birth (BW), weaning (WW) and yearling weight (YW) in Bali cattle.
A. Gunawan, R. Sari, Jakaria
doaj  

Single- and Multi-Trait Genome-Wide Association Analyses Identify the Genetic Loci and Candidate Genes for Growth Traits in Plecoglossus altivelis

Animals
With the rapid development of genomic big data and genome-wide association study technologies, massive genomic data are available for the genetic dissection, development and utilization of important economic traits.
Zhongyu Chang, Ao Chen, Shuo Liang, Chenling Ma, Tao Zhou, Yunfeng Zhao, Li Jiang   +6 more
doaj   +1 more source

Design and Analysis of Compression–Torsion Coupling Metamaterials Using the Golden Section Method

Advanced Engineering Materials, EarlyView.
A novel compression–torsion metamaterial is engineered using inclined rods and symmetry breaking. To optimize its torsional performance, the golden section method is employed. The mechanical response of the metamaterial is validated through both numerical analysis and experimental validation.
Amirhossein Hassani, Sara Bagherifard
wiley   +1 more source

Estimates of Direct and Maternal Genetic Effects on Birth and Weaning Weights in Salem Black Goats from India

Ruminants
Growth traits in goats are impacted by both genetic and non-genetic variables; as such, it is critical to separate direct and maternal effects for reliable genetic assessment.
Muralidharan Jaganadhan, Thiruvenkadan Aranganoor Kannan, Jayanthi Duraisamy, Adel Salah Khattab, Oludayo Michael Akinsola, Sunday Olusola Peters   +5 more
doaj   +1 more source