Interactions between the neuromodulatory systems and the amygdala: exploratory survey using the Allen Mouse Brain Atlas. [PDF]
, 2013 Neuromodulatory systems originate in nuclei localized in the subcortical region of the brain and control fundamental behaviors by interacting with many areas of the central nervous system.
Krichmar, Jeffrey L, Zaldivar, Andrew
core +1 more source
Regulatory conformational changes of the epsilon subunit in single FRET-labeled FoF1-ATP synthase [PDF]
arXiv, 2014 Subunit epsilon is an intrinsic regulator of the bacterial FoF1-ATP synthase, the ubiquitous membrane-embedded enzyme that utilizes a proton motive force in most organisms to synthesize adenosine triphosphate (ATP). The C-terminal domain of epsilon can extend into the central cavity formed by the alpha and beta subunits, as revealed by the recent X-ray
arxiv
Deciphering the Protein Motion of S1 Subunit in SARS-CoV-2 Spike Glycoprotein Through Integrated Computational Methods [PDF]
arXiv, 2020 The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major worldwide public health emergency that has infected over $1.5$ million people. The partially open state of S1 subunit in spike glycoprotein is considered vital for its infection with host cell and is represented as a key target for neutralizing antibodies.
arxiv
Unique features of Plasmids among different Citrobacter species [PDF]
, 2012 The _Citrobacter_ plasmids are supposed to represent the host genetic association within the living bacterial cell. The plasmids impart various beneficial characteristics to the host, helping it to retain suitable characteristics for adaptation as well ...
Swapnil G. Sanmukh, Waman N. Paunikar
core +1 more source
Bulk motion measurements in clusters of galaxies with ATHENA-like missions [PDF]
, 2013 The hierarchical formation of clusters of galaxies by accretion of material releases gravitational energy which dissipates into the intracluster gas. The process heats the material and generates gas turbulence and bulk motions and thus kinetic pressure.
arxiv +1 more source
Dental implantology and fibrous dysplasia: A 6‐year follow‐up case report and a literature review
Oral Surgery, Volume 16, Issue 1, Page 126-132, February 2023., 2023 Abstract Background and Aim It is unclear if fibrous dysplasia (FD) represents a contraindication for implant borne rehabilitation, and only two successful cases are reported in the literature with a 4–2‐year follow‐up. The present paper discusses this issue reporting a full‐arch maxillary rehabilitation with a >5‐year follow‐up.
Giuseppe Lizio +4 more
wiley +1 more source
Covalently bound substrate at the regulatory site triggers allosteric enzyme activation [PDF]
, 2008 The mechanism by which the enzyme pyruvate decarboxylase from yeast is activated allosterically has been elucidated. A total of seven three-dimensional structures of the enzyme, of enzyme variants or of enzyme complexes form two yeast species (three of ...
Georg Wille +5 more
core +1 more source
Ground States and Zero-Temperature Measures at the Boundary of Rotation Sets [PDF]
arXiv, 2016 We consider a continuous dynamical system $f:X\to X$ on a compact metric space $X$ equipped with an $m$-dimensional continuous potential $\Phi=(\phi_1,\cdots,\phi_m):X\to \bR^m$. We study the set of ground states $ GS(\alpha)$ of the potential $\alpha\cdot \Phi$ as a function of the direction vector $\alpha\in S^{m-1}$. %We also study the corresponding
arxiv
Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and TYK2 Inhibitors via IL10 Antagonism
Arthritis &Rheumatology, Accepted Article.Background JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but TYK2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn's Disease, which highlights the complex role for JAK‐STAT signaling in different inflammatory processes. In this study, we investigated
Sami Giryes +14 more
wiley +1 more source
Quantitative proteomic analysis of sphere-forming stem-like oral cancer cells. [PDF]
, 2013 IntroductionThe purpose of this study is to identify target proteins that may play important functional roles in oral cancer stem-like cells (CSCs) using mass spectrometry-based quantitative proteomics.MethodsSphere-formation assays were performed on ...
Feng, Sizhe +3 more
core +1 more source